Prenatal alcohol exposure is associated to different physical, behavioral, cognitive, and
neurological impairments collectively known as fetal alcohol spectrum disorder. The underlying …

Microvascular abnormalities, both in function and structure, lead to impaired tissue
perfusion that may affect multiple tissues and organs and seem to be involved in target-organ …

The aim of the present study was to analyze the possible involvement of vasoconstrictors
prostanoids on the reduced endothelium-dependent relaxations produced by chronic …

Fetal alcohol spectrum disorder is the main preventable cause of intellectual disability in the
Western world. Although binge drinking is the most studied prenatal alcohol exposure …

Aims This study examines the effect of endogenous male sex hormones on thromboxane A
2 (TXA 2 ), prostaglandin (PG) I 2 , PGF 2α , and PGE 2 release, as well as their role in …

Metabolic reprogramming is a hallmark of cancer. It has been described that breast cancer
subtypes present metabolism differences and this fact enables the possibility of using …

ATP-dependent potassium (K ATP ) channels are the target of multiple vasoactive factors
and drugs. Changes in the functional role of ATP-dependent (K ATP ) potassium channels in …

Neuronal NO plays a functional role in many vascular tissues, including MAs (mesenteric
arteries). Glucocorticoids alter NO release from endothelium and the CNS (central nervous …

Objective Experimental studies and opinion articles emphasize that cardiovascular
alterations associated with ageing can be improved by the long-term use of fenofibrates. We …

OBJECTIVE: We analysed the effect of aldosterone on calcitonin gene-related peptide (CGRP)
mediated vasodilation in noradrenaline precontracted endothelium denuded mesenteric …