Calcidiol, the major circulating metabolite of vitamin D, supports induction of pleiotropic
antimicrobial responses in vitro. Vitamin D supplementation elevates circulating calcidiol …

Background Sepsis continues to be a major cause of death, disability, and health-care
expenditure worldwide. Despite evidence suggesting that host genetics can influence sepsis …

Recent transcriptomic-based analysis of diffuse large B cell lymphoma (DLBCL) has highlighted
the clinical relevance of LN fibroblast and tumor-infiltrating lymphocyte (TIL) signatures …

Distinct phylogenetic lineages of Mycobacterium tuberculosis (MTB) cause disease in
patients of particular genetic ancestry, and elicit different patterns of cytokine and chemokine …

The human oral mucosa separates and protects deeper tissues and organs in the oral region
from the external environment. The main tissue components are a stratified squamous …

The tumour microenvironment plays a crucial role in the growth and progression of cancer,
and the presence of tumour-associated macrophages (TAMs) is associated with poor …

MIR137, transcribed as the microRNA miR-137, is one of the leading candidate schizophrenia
susceptibility genes to arise from large genome-wide association studies (GWAS) of the …

Tumor-associated macrophages (TAMs) are a highly plastic stromal cell type that support
cancer progression. Using single-cell RNA sequencing of TAMs from a spontaneous murine …

… 6 , Rosamond Nuamah …

Clonotypic αβ T cell responses to cargoes presented by major histocompatibility complex (MHC),
MR1, or CD1 proteins underpin adaptive immunity. Those responses are mostly …