Endoscopic endonasal versus transcranial approach to resection of olfactory groove meningiomas: a systematic review

A Purohit, R Jha, AM Khalafallah, C Price… - Neurosurgical …, 2020 - Springer
Despite the increasing utility of the endoscopic endonasal approach (EEA) for management
of anterior skull base (ASB) pathologies, the optimal treatment strategy for olfactory groove …

Targeting de novo lipid synthesis induces lipotoxicity and impairs DNA damage repair in glioblastoma mouse models

KM Eyme, A Sammarco, R Jha… - Science translational …, 2023 - science.org
Deregulated de novo lipid synthesis (DNLS) is a potential druggable vulnerability in
glioblastoma (GBM), a highly lethal and incurable cancer. Yet the molecular mechanisms that …

[PDF][PDF] Energy efficient particle swarm optimization based multipath routing in WSN

R Jha, S Ghosh - International journal online of science, 2018 - academia.edu
Wireless Networks includes a larger advantage in today’s communication application like
environmental, traffic, military, and health observation. To realize these applications it's …

[HTML][HTML] Transient ischemic stroke triggers sustained damage of the choroid plexus blood-CSF barrier

Y Chen, L Lin, MIH Bhuiyan, K He, R Jha… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Neuroinflammation is a pathological event associated with many neurological disorders,
including dementia and stroke. The choroid plexus (ChP) is a key structure in the ventricles of …

CSIG-17. SCD5 PROTECTS GLIOBLASTOMA STEM CELLS FROM DEATH AND DIFFERENTIATION BY MODULATING INTRACELLULAR LIPID COMPOSITION

H Mnatsakanyan, C Pechdimaljian, R Jha… - Neuro …, 2022 - academic.oup.com
Glioblastoma (GBM) is the most common malignant brain cancer in adults, enriched in a
small subpopulation of glioma stem cells (GSC), which can drive tumor recurrence and …

Divergent MEK/ERK and AMPK signaling dictate lipogenic plasticity and dependence on fatty acid synthesis in Glioblastoma

KM Eyme, A Sammarco, R Jha, H Mnatsakanyan… - bioRxiv, 2022 - biorxiv.org
Deregulated de novo lipid synthesis (DNLS) is a potential druggable vulnerability in
Glioblastoma (GBM), a highly lethal and incurable cancer. Yet the molecular mechanisms that …

TMET-02. Therapeutic Efficacy of a Novel Brain Penetrant SCD Inhibitor on Breast Cancer Brain Metastases

A Sammarco, K Eyme, R Jha, WDN Silva… - Neuro …, 2022 - ncbi.nlm.nih.gov
Brain metastases are a significant therapeutic challenge and are associated with high morbidity
and mortality. Recent evidence suggests that brain metastases have increased fatty acid …

TMET-25. MEK/ERK AND AMPK SIGNALING DICTATE VULNERABILITY TO FATTY ACID DESATURATION INHIBITION IN GLIOBLASTOMA

A Sammarco, K Eyme, R Jha, H Mnatsakanyan… - Neuro …, 2022 - ncbi.nlm.nih.gov
Lipid metabolism is altered in many cancers. Glioma stem cells (GSCs), a subpopulation
that contributes to molecular heterogeneity and therapeutic resistance of glioblastoma (GBM), …

[HTML][HTML] The endoscope-assisted supraorbital “keyhole” approach for anterior skull base meningiomas: an updated meta-analysis

DZ Khan, IS Muskens, RA Mekary… - Acta …, 2021 - Springer
Introduction The gold-standard treatment for symptomatic anterior skull base meningiomas
is surgical resection. The endoscope-assisted supraorbital “keyhole” approach (eSKA) is a …

Neural network modeling for groundwater-level forecasting in coastal aquifers

T Roshni, MK Jha, J Drisya - Neural Computing and Applications, 2020 - Springer
Advances in the artificial intelligence-based models can act as robust tools for modeling
hydrological processes. Neural network architectures coupled with learning algorithms are …