Oxidative stress, an imbalance toward the pro-oxidant side of the pro-oxidant/antioxidant
homeostasis, occurs in several human diseases. Among these diseases are those in which …

Oxidative/nitrosative stress, a pervasive condition of increased amounts of reactive oxygen/nitrogen
species, is now recognized to be a prominent feature of many acute and chronic …

Oxidative modifications of enzymes and structural proteins play a significant role in the
aetiology and/or progression of several human diseases. Protein carbonyl content is the most …

Carbonylation of proteins is an irreversible oxidative damage, often leading to a loss of
protein function, which is considered a widespread indicator of severe oxidative damage and …

S-Glutathionylation is the specific post-translational modification of protein cysteine
residues by the addition of the tripeptide glutathione, the most abundant and important low-molecular…

I. Introduction 00 II. Reactive Oxygen and Nitrogen Species 00 III. Biological Markers of
Oxidative/Nitrosative Stress 00 IV. Oxidative/Nitrosative Stress and Protein Modifications 00 A. …

Protein S-glutathionylation, the reversible formation of mixed disulfides between glutathione
and low-pK a cysteinyl residues, not only is a cellular response to mild oxidative/nitrosative …

Oxidative stress has been related increasingly to the onset and/or progression of a growing
number of human diseases. However, large studies on supplementation with anti-oxidants …

Actin is the major constituent of the cytoskeleton of almost all the eukaryotic cells. In vitro
experiments have indicated that oxidant-stressed nonmuscle mammalian cells undergo …

Nitrite and nitrate represent the final products of nitric oxide (NO) oxidation pathways, and
their hematic concentrations are frequently assessed as an index of systemic NO production. …