Assessment of sexual behavior in rats: The potentials and pitfalls

R Heijkoop, PT Huijgens, EMS Snoeren - Behavioural Brain Research, 2018 - Elsevier
In the field of behavioral neuroscience, it is essential to use the appropriate animal models
for the topic of investigation. Using the wrong model can result in false interpretation of the …

[HTML][HTML] Perinatal fluoxetine exposure changes social and stress-coping behavior in adult rats housed in a seminatural environment

DJ Houwing, R Heijkoop, JDA Olivier, EMS Snoeren - Neuropharmacology, 2019 - Elsevier
The use of selective serotonin reuptake inhibitors (SSRI) during pregnancy has increased
tremendously, but the consequences for the offspring remain largely unclear. Several studies …

[HTML][HTML] Third-party prosocial behavior in adult female rats is impaired after perinatal fluoxetine exposure

I Heinla, R Heijkoop, DJ Houwing, JDA Olivier… - Physiology & …, 2020 - Elsevier
SSRIs are commonly used to treat pregnant women with depression. However, SSRIs can
cross the placenta and affect the development of the fetus. The effects of perinatal SSRI …

[HTML][HTML] Changes in reward-induced neural activity upon Cafeteria Diet consumption

R Heijkoop, JF Lalanza, M Solanas… - Physiology & …, 2024 - Elsevier
Excessive consumption of highly palatable foods rich in sugar and fat, often referred to as “junk”
or “fast” foods, plays a central role in the development of obesity. The highly palatable …

[HTML][HTML] Silencing and stimulating the medial amygdala impairs ejaculation but not sexual incentive motivation in male rats

PT Huijgens, R Heijkoop, EMS Snoeren - Behavioural Brain Research, 2021 - Elsevier
The medial amygdala (MeA) is a sexually dimorphic brain region that integrates sensory
information and hormonal signaling, and is involved in the regulation of social behaviors. …

[HTML][HTML] CaMKIIa+ neurons in the bed nucleus of the stria terminalis modulate pace of natural reward seeking depending on internal state

PT Huijgens, R Heijkoop, LJMJ Vanderschuren… - …, 2024 - Springer
This study aims to investigate the underlying neurobiological mechanisms that regulate natural
reward seeking behaviors, specifically in the context of sexual behavior and sucrose self-…

Sexual incentive motivation

PT Huijgens, R Heijkoop, EMS Snoeren - Animal models of Reproductive …, 2023 - Springer
Motivation can be described as the processes that activate, direct, and determine the
persistence of goal-directed behavior. A certain level of sexual motivation is required to activate …

Functional dyspepsia and irritable bowel syndrome in patients with achalasia and its association with non-cardiac chest pain and a decreased health-related quality of …

…, MA Van Herwaarden, R Heijkoop… - Scandinavian journal …, 2009 - Taylor & Francis
Objective. In patients with achalasia, little is known about symptoms of the gastrointestinal
tract other than the esophagus. The purpose of this study was to determine the prevalence of …

[HTML][HTML] Female rat sexual behavior is unaffected by perinatal fluoxetine exposure

…, DJ Houwing, JDA Olivier, R Heijkoop… - …, 2020 - Elsevier
Serotonin plays an important role in adult female sexual behavior, however little is known
about the influence of serotonin during early development on sexual functioning in adulthood. …

[HTML][HTML] Effects of perinatal fluoxetine exposure on novelty-induced social and non-social investigation behaviors in a seminatural environment

…, I Heinla, DJ Houwing, JDA Olivier, R Heijkoop… - …, 2021 - Springer
Selective serotonin reuptake inhibitors (SSRIs) are increasingly prescribed as medication
for various affective disorders during pregnancy. SSRIs cross the placenta and affect …