Recent reports demonstrate T-cell infiltration of adipose tissue in early obesity. We hypothesized
that interferon (IFN) γ, a major T-cell inflammatory cytokine, would attenuate human …

Conjugated linoleic acids (CLAs) are conjugated dienoic isomers of linoleic acid. Many people
supplement their diets with CLAs to attempt weight loss, and the trans-10,cis-12 isomer (…

Chemokine (CC motif) ligand 2 (CCL2), initially identified as monocyte chemoattractant
protein-1 (MCP-1), recruits immune cells to the central nervous system (CNS) during …

Background Increased inflammation has been well defined in coronavirus disease 2019 (COVID-19),
while definitive pathways driving severe forms of this disease remain uncertain. …

Increasing physical activity and decreasing sedentary behavior are associated with a higher
quality of life and lower mortality rates for cancer survivors, a growing population group. …

Background Clinicians vary markedly in their ability to detect murmurs during cardiac
auscultation and identify the underlying pathological features. Deep learning approaches have …

Adipocyte differentiation is controlled by many transcription factors, but few known downstream
targets of these factors are necessary for adipogenesis. Here we report that retinol …

Objective— We investigated atheroprotective properties of apolipoprotein (apo) E beyond its
ability to lower plasma cholesterol. We hypothesized that apoE reduces atherosclerosis by …

The design of a 4-way SIMD streaming data processor emphasizes achievable performance
in area and power. Software controls data movement and instruction flow, and improves …

Background Increased inflammation is a hallmark of COVID-19, with pulmonary and systemic
inflammation identified in multiple cohorts of patients. Definitive cellular and molecular …