User profiles for Roy Moscona

Roy Moscona

Research Fellow, Cincinnati's Children's Hospital
Verified email at cchmc.org
Cited by 85

Comparison between next‐generation and Sanger‐based sequencing for the detection of transmitted drug‐resistance mutations among recently infected HIV‐1 …

R Moscona, D Ram, M Wax, E Bucris… - Journal of the …, 2017 - Wiley Online Library
Introduction: Transmitted drug‐resistance mutations (TDRM) may hamper successful anti‐HIV‐1
therapy and impact future control of the HIV‐1 epidemic. Recently infected, therapy‐…

[HTML][HTML] BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells

SM Janssen, R Moscona, M Elchebly… - Cell death …, 2020 - nature.com
Melanoma is among the most aggressive cancers due to its tendency to metastasize early.
Phenotype switching between a proliferative and an invasive state has been suggested as a …

HCV genotype-1 subtypes and resistance-associated substitutions in drug-naive and in direct-acting antiviral treatment failure patients

Y Gozlan, Z Ben-Ari, R Moscona, R Shirazi… - Antiviral …, 2017 - journals.sagepub.com
Background Direct-acting antiviral (DAA) treatment regimens and response rates of patients
with HCV genotype-1 (GT1) are currently considered subtype-dependent. Identification of …

BORIS/CTCFL‐mediated chromatin accessibility alterations promote a pro‐invasive transcriptional signature in melanoma cells

R Moscona, SM Janssen, M Elchebly… - Pigment Cell & …, 2023 - Wiley Online Library
Melanoma is the deadliest form of skin cancer, due to its tendency to metastasize early.
Brother of regulator of imprinted sites (BORIS), also known as CCCTC binding factor‐like (CTCFL…

Immune clustering reveals molecularly distinct subtypes of lung adenocarcinoma

Y Lender, O Givton, R Bornshten, M Azar, R Moscona… - bioRxiv, 2023 - biorxiv.org
Lung adenocarcinoma, the most prevalent type of non-small cell lung cancer, consists of two
driver mutations in KRAS or EGFR. In general, these mutations are mutually exclusive, and …

[PDF][PDF] ATAC-Seq and RNA-Seq combined analysis elucidates the impact of BORIS/CTCFL on melanoma progression, mediated by chromatin accessibility and gene …

R Moscona, SM Janssen, M Elchebly, AI Papadakis… - scholar.archive.org
Melanoma accounts for most deaths form skin cancer, since it metastasizes early, and it
usually diagnosed at an advance stage. Brother of Regulator of Imprinted Sites (BORIS), also …

A17 Transmitted drug-resistant mutations among recently infected HIV-1 patients in Israel, 2000–2014

R Moscona, D Ram, M Wax, E Bucris, I Levy… - Virus …, 2018 - academic.oup.com
Transmitted drug-resistant mutations (TDRM) may hamper successful anti-HIV-1 therapy
and impact future control of the HIV-1 epidemic. Recently infected, therapy-naïve individuals …

[PDF][PDF] 22nd International BioInformatics Workshop on Virus Evolution and Molecular Epidemiology| S7

R Moscona, D Ram, M Wax, E Bucris, I Levy… - pdfs.semanticscholar.org
cent) were successfully genotyped: HIV-1 subtype C was the most prevalent (97 per cent),
followed by subtype A1 (1.2 per cent), Page 1 cent) were successfully genotyped: HIV-1 …

[PDF][PDF] A19 The impact of HIV-1 on the evolution of Mycobacterium tuberculosis

A Koch, D Brites, D Stucki, JC Evans, R Seldon… - Virus …, 2018 - academic.oup.com
nonsynonymous substitutions within HIV-1 infected individuals. Among the 25,251 polymorphic
codon sites analysed, FUBAR revealed that 189-fold more were detectably evolving …

A18 HIV-1 genetic diversity and drug resistance in Haiti

G Delva, M Charles, C Yang - Virus Evolution, 2018 - academic.oup.com
HIV-1 subtype B appears to be the most genetically diverse AIDS virus in Haiti. However,
there have been few phylogenetic analyses on circulating drug-resistant HIV-1 strains. The …