ICP27 mediates HSV RNA export by shuttling through a leucine-rich nuclear export signal and binding viral intronless RNAs through an RGG motif
RM Sandri-Goldin - Genes & development, 1998 - genesdev.cshlp.org
Infection of metazoan cells with some viruses alters the balance of cellular mRNA export to
favor viral RNA export and to retain cellular transcripts in the nucleus. Here, evidence is …
favor viral RNA export and to retain cellular transcripts in the nucleus. Here, evidence is …
Evidence that the herpes simplex virus immediate early protein ICP27 acts post-transcriptionally during infection to regulate gene expression
IL Smith, MA Hardwicke, RM Sandri-Goldin - Virology, 1992 - Elsevier
The herpes simplex virus (HSV-1) immediate early protein ICP27 is a regulatory protein
which is essential for virus replication. The phenotype of temperature-sensitive and deletion …
which is essential for virus replication. The phenotype of temperature-sensitive and deletion …
[HTML][HTML] Herpes simplex virus blocks host transcription termination via the bimodal activities of ICP27
Infection by viruses, including herpes simplex virus-1 (HSV-1), and cellular stresses cause
widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII) in …
widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII) in …
[PDF][PDF] The many roles of the regulatory protein ICP27 during herpes simplex virus infection
RM Sandri-Goldin - Front Biosci, 2008 - article.imrpress.com
1. Abstract 2. Introduction 3. Post-transcriptional activities of ICP27 3.1. Pre-mRNA splicing
inhibition 3.2. The role of ICP27 in 3’end formation 3.3. ICP27 and the export of viral mRNA …
inhibition 3.2. The role of ICP27 in 3’end formation 3.3. ICP27 and the export of viral mRNA …
HSV‐1 ICP 27 targets the TBK 1‐activated STING signalsome to inhibit virus‐induced type I IFN expression
Herpes simplex virus ( HSV ) 1 stimulates type I IFN expression through the cGAS – STING –
TBK 1 signaling axis. Macrophages have recently been proposed to be an essential source …
TBK 1 signaling axis. Macrophages have recently been proposed to be an essential source …
[HTML][HTML] ICP27 interacts with SRPK1 to mediate HSV splicing inhibition by altering SR protein phosphorylation
KS Sciabica, QJ Dai, RM Sandri‐Goldin - The EMBO journal, 2003 - embopress.org
Infection with some viruses can alter cellular mRNA processing to favor viral gene
expression. We present evidence that herpes simplex virus 1 (HSV‐1) protein ICP27, which …
expression. We present evidence that herpes simplex virus 1 (HSV‐1) protein ICP27, which …
A herpesvirus regulatory protein appears to act post-transcriptionally by affecting mRNA processing.
RM Sandri-Goldin, GE Mendoza - Genes & Development, 1992 - genesdev.cshlp.org
Post-transcriptional control mechanisms play an important role in regulating gene expression
for a number of viruses, especially in the regulation of late gene products. In this study we …
for a number of viruses, especially in the regulation of late gene products. In this study we …
ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway
IHB Chen, KS Sciabica, RM Sandri-Goldin - Journal of virology, 2002 - Am Soc Microbiol
Herpes simplex virus type 1 (HSV-1) protein ICP27 facilitates the export of viral intronless
mRNAs. ICP27 shuttles between the nucleus and cytoplasm, which has been shown to require …
mRNAs. ICP27 shuttles between the nucleus and cytoplasm, which has been shown to require …
The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection
MA Hardwicke, RM Sandri-Goldin - Journal of virology, 1994 - Am Soc Microbiol
We have previously shown that the herpes simplex virus immediate-early regulatory protein
ICP27 acts posttranscriptionally to affect mRNA processing (RM Sandri-Goldin and GE …
ICP27 acts posttranscriptionally to affect mRNA processing (RM Sandri-Goldin and GE …
[PDF][PDF] Viral vectors for neural circuit mapping and recent advances in trans-synaptic anterograde tracers
Viral tracers are important tools for neuroanatomical mapping and genetic payload delivery.
Genetically modified viruses allow for cell-type-specific targeting and overcome many …
Genetically modified viruses allow for cell-type-specific targeting and overcome many …