User profiles for Ruben Portugues

Ruben Portugues

Technical University of Munich
Verified email at tum.de
Cited by 5756

[HTML][HTML] Adaptive locomotor behavior in larval zebrafish

R Portugues, F Engert - Frontiers in systems neuroscience, 2011 - frontiersin.org
In this study we report that larval zebrafish display adaptive locomotor output that can be
driven by unexpected visual feedback. We develop a new assay that addresses visuomotor …

[PDF][PDF] Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior

R Portugues, CE Feierstein, F Engert, MB Orger - Neuron, 2014 - cell.com
Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …

The neural basis of visual behaviors in the larval zebrafish

R Portugues, F Engert - Current opinion in neurobiology, 2009 - Elsevier
We review visually guided behaviors in larval zebrafish and summarise what is known
about the neural processing that results in these behaviors, paying particular attention to the …

Optogenetics in a transparent animal: circuit function in the larval zebrafish

R Portugues, KE Severi, C Wyart, MB Ahrens - Current opinion in …, 2013 - Elsevier
Optogenetic tools can be used to manipulate neuronal activity in a reversible and specific
manner. In recent years, such methods have been applied to uncover causal relationships …

Ontogeny of classical and operant learning behaviors in zebrafish

A Valente, KH Huang, R Portugues… - Learning & …, 2012 - learnmem.cshlp.org
The performance of developing zebrafish in both classical and operant conditioning assays
was tested with a particular focus on the emergence of these learning behaviors during …

[HTML][HTML] Neural control and modulation of swimming speed in the larval zebrafish

KE Severi, R Portugues, JC Marques, DM O'Malley… - Neuron, 2014 - cell.com
Vertebrate locomotion at different speeds is driven by descending excitatory connections to
central pattern generators in the spinal cord. To investigate how these inputs determine …

[HTML][HTML] Putting a finishing touch on GECIs

T Rose, PM Goltstein, R Portugues… - Frontiers in molecular …, 2014 - frontiersin.org
More than a decade ago genetically encoded calcium indicators (GECIs) entered the stage
as new promising tools to image calcium dynamics and neuronal activity in living tissues and …

Optimization of a GCaMP calcium indicator for neural activity imaging

…, XR Sun, A Gordus, MB Orger, R Portugues… - Journal of …, 2012 - Soc Neuroscience
Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience.
Recent efforts in protein engineering have significantly increased the performance of …

Brain-wide neuronal dynamics during motor adaptation in zebrafish

…, DN Robson, AF Schier, F Engert, R Portugues - Nature, 2012 - nature.com
A fundamental question in neuroscience is how entire neural circuits generate behaviour
and adapt it to changes in sensory feedback. Here we use two-photon calcium imaging to …

Whole-brain activity mapping onto a zebrafish brain atlas

…, D Schoppik, JE Fitzgerald, R Portugues… - Nature …, 2015 - nature.com
In order to localize the neural circuits involved in generating behaviors, it is necessary to
assign activity onto anatomical maps of the nervous system. Using brain registration across …