User profiles for Ruddi Rodriguez-Garcia

Ruddi Rodriguez-Garcia

Utrecht University
Verified email at uu.nl
Cited by 752

[PDF][PDF] Direct cytoskeleton forces cause membrane softening in red blood cells

R Rodríguez-García, I López-Montero, M Mell, G Egea… - Biophysical journal, 2015 - cell.com
Erythrocytes are flexible cells specialized in the systemic transport of oxygen in vertebrates.
This physiological function is connected to their outstanding ability to deform in passing …

Polymersomes: smart vesicles of tunable rigidity and permeability

R Rodriguez-Garcia, M Mell, I López-Montero, J Netzel… - Soft matter, 2011 - pubs.rsc.org
We report an experimental study on the mechanical and permeability properties of giant
polymersomes made of diblock (PBD–PEO) and triblock (PEO–PPO–PEO) copolymers. These …

[PDF][PDF] CLASP suppresses microtubule catastrophes through a single TOG domain

…, A Sharma, A Rai, N Olieric, R Rodriguez-Garcia… - Developmental cell, 2018 - cell.com
The dynamic instability of microtubules plays a key role in controlling their organization and
function, but the cellular mechanisms regulating this process are poorly understood. Here, …

EB1 interacts with outwardly curved and straight regions of the microtubule lattice

A Guesdon, F Bazile, RM Buey, R Mohan, S Monier… - Nature cell …, 2016 - nature.com
EB1 is a microtubule plus-end tracking protein that recognizes GTP-tubulin dimers in
microtubules 1 , 2 , 3 , 4 and thus represents a unique probe to investigate the architecture of the …

[PDF][PDF] Termination of protofilament elongation by eribulin induces lattice defects that promote microtubule catastrophes

H Doodhi, AE Prota, R Rodríguez-García, H Xiao… - Current Biology, 2016 - cell.com
Microtubules are dynamic polymers built of tubulin dimers that attach in a head-to-tail
fashion to form protofilaments, which further associate laterally to form a tube. Asynchronous …

[PDF][PDF] Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules

R Rodríguez-García, VA Volkov, CY Chen… - Current Biology, 2020 - cell.com
Microtubule-dependent organization of membranous organelles occurs through motor-based
pulling and by coupling microtubule dynamics to membrane remodeling. For example, …

Taxanes convert regions of perturbed microtubule growth into rescue sites

…, J Estévez-Gallego, R Rodríguez-García… - Nature Materials, 2020 - nature.com
Microtubules are polymers of tubulin dimers, and conformational transitions in the microtubule
lattice drive microtubule dynamic instability and affect various aspects of microtubule …

Dissipative dynamics of fluid lipid membranes enriched in cholesterol

LR Arriaga, R Rodríguez-García, LH Moleiro… - Advances in Colloid and …, 2017 - Elsevier
Cholesterol is an intriguing component of fluid lipid membranes: It makes them stiffer but
also more fluid. Despite the enormous biological significance of this complex dynamical …

The polarity-induced force imbalance in Caenorhabditis elegans embryos is caused by asymmetric binding rates of dynein to the cortex

R Rodriguez-Garcia, L Chesneau… - Molecular Biology of …, 2018 - Am Soc Cell Biol
During asymmetric cell division, the molecular motor dynein generates cortical pulling forces
that position the spindle to reflect polarity and adequately distribute cell fate determinants. …

Nonlinear dilational mechanics of Langmuir lipid monolayers: a lateral diffusion mechanism

LR Arriaga, I López-Montero, R Rodríguez-García… - Physical Review E, 2008 - APS
We propose a theoretical model for the nonlinear mechanical response of Langmuir lipid
monolayers subjected to a dilational in-plane deformation. Lateral diffusion in conjunction with …