The sheep genome illuminates biology of the rumen and lipid metabolism
Sheep (Ovis aries) are a major source of meat, milk, and fiber in the form of wool and represent
a distinct class of animals that have a specialized digestive organ, the rumen, that carries …
a distinct class of animals that have a specialized digestive organ, the rumen, that carries …
[HTML][HTML] Coordinated international action to accelerate genome-to-phenome with FAANG, the Functional Annotation of Animal Genomes project
…, L Andersson, AL Archibald, CD Bottema, R Brauning… - Genome biology, 2015 - Springer
We describe the organization of a nascent international effort, the Functional Annotation of
Animal Genomes (FAANG) project, whose aim is to produce comprehensive maps of …
Animal Genomes (FAANG) project, whose aim is to produce comprehensive maps of …
Resolving the evolution of extant and extinct ruminants with high-throughput phylogenomics
…, JC McEwan, R Brauning… - Proceedings of the …, 2009 - National Acad Sciences
The Pecorans (higher ruminants) are believed to have rapidly speciated in the Mid-Eocene,
resulting in five distinct extant families: Antilocapridae, Giraffidae, Moschidae, Cervidae, and …
resulting in five distinct extant families: Antilocapridae, Giraffidae, Moschidae, Cervidae, and …
[HTML][HTML] Construction of relatedness matrices using genotyping-by-sequencing data
Background Genotyping-by-sequencing (GBS) is becoming an attractive alternative to array-based
methods for genotyping individuals for a large number of single nucleotide …
methods for genotyping individuals for a large number of single nucleotide …
Linkage disequilibrium over short physical distances measured in sheep using a high‐density SNP chip
…, R Bunch, R McCulloch, BJ Hayes, R Brauning… - Animal …, 2014 - Wiley Online Library
The extent of linkage disequilibrium ( LD ) between genetic loci has implications for both
association studies and the accuracy of genomic prediction. To characterise the persistence of …
association studies and the accuracy of genomic prediction. To characterise the persistence of …
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases
RR Handley, SJ Reid, R Brauning… - Proceedings of the …, 2017 - National Acad Sciences
The neurodegenerative disorder Huntington’s disease (HD) is typically characterized by
extensive loss of striatal neurons and the midlife onset of debilitating and progressive chorea, …
extensive loss of striatal neurons and the midlife onset of debilitating and progressive chorea, …
[HTML][HTML] Sheep genome functional annotation reveals proximal regulatory elements contributed to the evolution of modern breeds
…, A Reverter, M Perez-Enciso, R Brauning… - Nature …, 2018 - nature.com
Domestication fundamentally reshaped animal morphology, physiology and behaviour, offering
the opportunity to investigate the molecular processes driving evolutionary change. Here …
the opportunity to investigate the molecular processes driving evolutionary change. Here …
[HTML][HTML] SNPchiMp v. 3: integrating and standardizing single nucleotide polymorphism data for livestock species
…, G Evans, B Simpson, G Tosser-Klopp, R Brauning… - BMC genomics, 2015 - Springer
Background In recent years, the use of genomic information in livestock species for genetic
improvement, association studies and many other fields has become routine. In order to …
improvement, association studies and many other fields has become routine. In order to …
[HTML][HTML] A physical map of the bovine genome
Background Cattle are important agriculturally and relevant as a model organism. Previously
described genetic and radiation hybrid (RH) maps of the bovine genome have been used …
described genetic and radiation hybrid (RH) maps of the bovine genome have been used …
[HTML][HTML] Whole Genome Sequencing for Determining the Source of Mycobacterium bovis Infections in Livestock Herds and Wildlife in New Zealand
M Price-Carter, R Brauning, GW De Lisle… - Frontiers in Veterinary …, 2018 - frontiersin.org
The ability to DNA fingerprint Mycobacterium bovis isolates helped to define the role of
wildlife in the persistence of bovine tuberculosis in New Zealand. DNA fingerprinting results …
wildlife in the persistence of bovine tuberculosis in New Zealand. DNA fingerprinting results …