Twenty‐eight children referred with a preliminary diagnosis of autistic disorder under age 3
yrs were extensively examined from the neuropsychiatric point of view and followed up for …

Intake of processed foods has increased markedly over the past decades, coinciding with
increased microvascular diseases such as chronic kidney disease (CKD) and diabetes. Here, …

Cargo sequestration is a fundamental step of selective autophagy in which cells generate a
double-membrane structure termed an "autophagosome" on the surface of cargoes. NDP52, …

Diabetic kidney disease is one of the major microvascular complications of both type 1 and
type 2 diabetes mellitus. Approximately 30% of patients with diabetes experience renal …

The sequestration of damaged mitochondria within double-membrane structures termed
autophagosomes is a key step of PINK1/Parkin mitophagy. The ATG4 family of proteases are …

Objective: To study the prevalence of tuberous sclerosis in children and adolescents. Design:
Previously published diagnostic criteria for tuberous sclerosis were used. All physicians …

Mitochondrial stress has been widely observed in diabetic kidney disease (DKD). Cyclophilin
D (CypD) is a functional component of the mitochondrial permeability transition pore (mPTP…

Life expectancy has been examined from a variety of perspectives in recent history. Epidemiology
is one perspective which examines causes of morbidity and mortality at the population …

Background The nicotinamide adenine dinucleotide phosphate oxidase isoform 4 (Nox4)
mediates reactive oxygen species (ROS) production and renal fibrosis in diabetic kidney …

Purpose Methylglyoxal, a by-product of glycolysis and a precursor in the formation of advanced
glycation end-products, is significantly elevated in the diabetic myocardium. Therefore, …