The respiratory megacomplex represents the highest-order assembly of respiratory chain
complexes, and it allows mitochondria to respond to energy-requiring conditions. To …

Respiration is one of the most vital and basic features of living organisms. In mammals,
respiration is accomplished by respiratory chain complexes located on the mitochondrial inner …

The respiratory chain complexes I, III and IV (CI, CIII and CIV) are present in the bacterial
membrane or the inner mitochondrial membrane and have a role of transferring electrons and …

The mitochondrial adenosine triphosphate (ATP) synthase produces most of the ATP required
by mammalian cells. We isolated porcine tetrameric ATP synthase and solved its structure …

Mitochondrial Ca2+ homeostasis regulates energy production, cell division, and cell death.
The basic properties of mitochondrial Ca2+ uptake have been firmly established. The Ca2+ …

The mammalian respiratory chain complexes assemble into supercomplexes (SCs) and
reside in the inner mitochondrial membrane to transfer electrons and establish the proton …

Respiration is one of the most basic features of living organisms, and the electron transport
chain complexes are probably the most complicated protein system in mitochondria. Complex…

Respirasome, a huge molecular machine that carries out cellular respiration, has gained
growing attention since its discovery, because respiration is the most indispensable biological …

Serine beta-lactamase-like protein (LACTB) is a mammalian mitochondrial serine protease
that can specifically hydrolyze peptide bonds adjacent to aspartic acid residues and is …

Mammalian respiratory complex I (CI) is a 45-subunit, redox-driven proton pump that generates
an electrochemical gradient across the mitochondrial inner membrane to power ATP …