User profiles for Ruoxuan Sun
Ruoxuan SunTakeda Pharmaceuticals USA Verified email at takeda.com Cited by 285 |
[HTML][HTML] Glycosylation of immune receptors in cancer
Evading host immune surveillance is one of the hallmarks of cancer. Immune checkpoint
therapy, which aims to eliminate cancer progression by reprogramming the antitumor immune …
therapy, which aims to eliminate cancer progression by reprogramming the antitumor immune …
Optical properties of chemical vapor deposition-grown PtSe2 characterized by spectroscopic ellipsometry
…, D Zhang, XQ Yan, M Ren, X Zhao, F Liu, R Sun… - 2D …, 2019 - iopscience.iop.org
PtSe 2, an emerging 2D group-10 transition metal dichalcogenide (TMD), has aroused
significant attention recently due to its intriguing physical properties. Here, the optical properties …
significant attention recently due to its intriguing physical properties. Here, the optical properties …
Saccharide analog, 2‐deoxy‐d‐glucose enhances 4‐1BB‐mediated antitumor immunity via PD‐L1 deglycosylation
Triple‐negative breast cancer (TNBC) lacks a well‐defined molecular target and is associated
with poorer outcomes compared to other breast cancer subtypes. Programmed cell death …
with poorer outcomes compared to other breast cancer subtypes. Programmed cell death …
Improved Interfacial Ion Migration and Deposition through the Chain‐Liquid Synergistic Effect by a Carboxylated Hydrogel Electrolyte for Stable Zinc Metal Anodes
C Tian, J Wang, R Sun, T Ali, H Wang… - Angewandte Chemie …, 2023 - Wiley Online Library
The large‐scale applicability of Zn‐metal anodes is severely impeded by the issues such as
the dendrite growth, complicated hydrogen evolution, and uncontrollable passivation …
the dendrite growth, complicated hydrogen evolution, and uncontrollable passivation …
[HTML][HTML] Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity
Hepatocellular carcinoma (HCC) accounts for most of primary liver cancer, of which five-year
survival rate remains low and chemoprevention has become a strategy to reduce disease …
survival rate remains low and chemoprevention has become a strategy to reduce disease …
Exogenous microbiota-derived metabolite trimethylamine N-oxide treatment alters social behaviors: Involvement of hippocampal metabolic adaptation
…, G Zhang, Y Su, Q Wang, Q Wang, Y Wang, R Sun… - …, 2021 - Elsevier
Increasing evidence indicates that gut microbiota and its metabolites can influence the brain
function and the related behaviors. Trimethylamine N-oxide (TMAO), an indirect metabolite …
function and the related behaviors. Trimethylamine N-oxide (TMAO), an indirect metabolite …
The antimetastatic effect and underlying mechanisms of thioredoxin reductase inhibitor ethaselen
X Zheng, Y Chen, M Bai, Y Liu, B Xu, R Sun… - Free Radical Biology and …, 2019 - Elsevier
Treating cancer metastasis is of vital importance to prolong patients’ survival. Thioredoxin
reductase (TrxR) is overexpressed in many cancer types and has been recognized as an anti-…
reductase (TrxR) is overexpressed in many cancer types and has been recognized as an anti-…
[HTML][HTML] Role of thioredoxin reductase 1 in dysplastic transformation of human breast epithelial cells triggered by chronic oxidative stress
C Dong, L Zhang, R Sun, J Liu, H Yin, X Li, X Zheng… - Scientific reports, 2016 - nature.com
Thioredoxin reductase 1 (TrxR1) is a pivotal intracellular redox sensor and antioxidant
enzyme. On the other hand, overexpression of TrxR1 is closely correlated with the initiation of …
enzyme. On the other hand, overexpression of TrxR1 is closely correlated with the initiation of …
[HTML][HTML] Thioredoxin reductase as a novel and efficient plasma biomarker for the detection of non-small cell lung cancer: a large-scale, multicenter study
S Ye, X Chen, Y Yao, Y Li, R Sun, H Zeng, Y Shu… - Scientific reports, 2019 - nature.com
There is an increased demand for efficient biomarkers for the diagnosis of non-small cell
lung cancer (NSCLC). This study aimed to evaluate plasma levels of TrxR activity in a large …
lung cancer (NSCLC). This study aimed to evaluate plasma levels of TrxR activity in a large …
Synergistic inhibition of sunitinib and ethaselen against human colorectal cancer cells proliferation
Sunitinib, a multi-targeted tyrosine kinase inhibitor, has been widely used in the therapy of
advanced renal cell cancer and imatinib-resistant gastrointestinal stromal tumors. However, …
advanced renal cell cancer and imatinib-resistant gastrointestinal stromal tumors. However, …