The task of rapidly identifying patients infected with Mycobacterium tuberculosis in resource-constrained
environments remains a challenge. A sensitive and robust platform that does …

RNA-seq technologies have provided significant insight into the transcription networks of
mycobacteria. However, such studies provide no definitive information on the translational …

Goal: The aim of the study herein reported was to review mobile health (mHealth) technologies
and explore their use to monitor and mitigate the effects of the COVID-19 pandemic. …

Single-cell methodologies and technologies have started a revolution in biology which until
recently has primarily been limited to deep sequencing and imaging modalities. With the …

Signaling pathways are orchestrated by post-translational modifications (PTMs) such as
phosphorylation. However, pathway analysis of PTM data sets generated by mass spectrometry (…

HIV-1 infection of CD4 + T cells leads to cytopathic effects and cell demise, which is counter
to the observation that certain HIV-1-infected cells possess a remarkable long-term stability …

One key to the success of Mycobacterium tuberculosis as a pathogen is its ability to reside
in the hostile environment of the human macrophage. Bacteria adapt to stress through a …

Astrocyte elevated gene‐1 (AEG‐1) is a key contributor to hepatocellular carcinoma (HCC)
development and progression. To enhance our understanding of the role of AEG‐1 in …

The type VII secretion systems are conserved across mycobacterial species and in many
Gram-positive bacteria. While the well-characterized Esx-1 pathway is required for the …

10.7554/eLife.20420.001 Antibiotic resistance arising via chromosomal mutations is typically
specific to a particular antibiotic or class of antibiotics. We have identified mutations in …