Lung cancer is a malignant lung tumor with various histological variants that arise from different
cell types, such as bronchial epithelium, bronchioles, alveoli, or bronchial mucous glands…

Nucleic acid aptamers are becoming popular as molecular probes for identification and
imaging pathology and, at the same time, as a convenient platform for targeted therapy. Recent …

Aptamers are short, single-stranded DNA or RNA oligonucleotide molecules that function as
synthetic analogs of antibodies and bind to a target molecule with high specificity. Aptamer …

Breast cancer (BC) diagnostics lack noninvasive methods and procedures for screening and
monitoring disease dynamics. Admitted CellSearch® is used for fluid biopsy and capture of …

Cisplatin is an effective drug for treating various cancer types. However, it is highly toxic for
both healthy and tumor cells. Therefore, there is a need to reduce its therapeutic dose and …

SNP genotyping based on the reaction of specific primer extension with the following
bioluminescent detection of its products was shown to be potentially applicable for biomedical …

Here, we present DNA aptamers capable of specific binding to glial tumor cells in vitro, ex
vivo, and in vivo for visualization diagnostics of central nervous system tumors. We selected …

Background Neoadjuvant or adjuvant immunotherapy can improve outcomes in patients
with resectable non–small-cell lung cancer (NSCLC). Perioperative regimens may combine …

Background The first interim analysis of the KEYNOTE-564 study showed improved disease-free
survival with adjuvant pembrolizumab compared with placebo after surgery in patients …

Background Systemic therapies have improved the management of hepatocellular carcinoma,
but there is still a need to further enhance overall survival in first-line advanced stages. …