MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As part
of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) project, …

Schizophrenia is one of the most widespread and complex mental disorders. To
characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing (snRNA-seq) …

A deeper knowledge of the dynamic transcriptional activity of promoters and enhancers is
needed to improve mechanistic understanding of the pathogenesis of heart failure and heart …

The glandular stomach is composed of two regenerative compartments termed corpus and
antrum, and our understanding of the transcriptional networks that maintain these tissues is …

In birds, sex is genetically determined; however, the molecular mechanism is not well-understood.
The avian Z sex chromosome (chrZ) lacks whole chromosome inactivation, in contrast …

Cap Analysis of Gene Expression (CAGE) in combination with single-molecule sequencing
technology allows precision mapping of transcription start sites (TSSs) and genome-wide …

The development of craniofacial skeletal structures is fascinatingly complex and elucidation
of the underlying mechanisms will not only provide novel scientific insights, but also help …

In this study we use comparative genomics to uncover a gene with uncharacterized function
(1700011H14Rik/C14orf105/CCDC198), which we hereby name FAME (Factor Associated …

We present a novel modification of genetic algorithm (GA) which determines personalized
parameters of cardiomyocyte electrophysiology model based on set of experimental human …

Non-biting midges (Chironomidae) are known to inhabit a wide range of environments, and
certain species can tolerate extreme conditions, where the rest of insects cannot survive. In …