Recent developments in the area of biological detection by optical sensing of molecular
oxygen (O2) are reviewed, with particular emphasis on the quenched-phosphorescence O2 …

In recent years, significant progress has been achieved in the sensing and imaging of
molecular oxygen (O 2 ) in biological samples containing live cells and tissue. We review recent …

Recent years have witnessed the development of an enormous variety of hydrogel-based
systems for neuroregeneration. Formed from hydrophilic polymers and comprised of up to 90…

Monitoring cell and tissue oxygenation is important for the analysis of cell development and
differentiation, mitochondrial function, and common (patho)physiological conditions such as …

High brightness, chemical and photostability, tunable characteristics, and spectral and surface
properties are important attributes for nanoparticle probes designed for live cell imaging. …

Background Oxygen and glucose metabolism play pivotal roles in many (patho)physiological
conditions. In particular, oxygen and glucose deprivation (OGD) during ischemia and …

Spheroids are three-dimensional cellular models with widespread basic and translational
application across academia and industry. However, methodological transparency and …

Multicellular spheroids are useful models of mammalian tissue for studies of cell proliferation,
differentiation, replacement therapies and drug action. Having a size of 100–500 μm they …

Monitoring of oxygenation is important for physiological experiments investigating the
growth, differentiation and function of individual cells in 3D tissue models. Phosphorescence …

Stem cells and the niche in which they reside feature a complex microenvironment with
tightly regulated homeostasis, cell-cell interactions and dynamic regulation of metabolism. A …