There is increasing interest in the use of edited proton magnetic resonance spectroscopy for
the detection of GABA in the human brain. At a recent meeting held at Cardiff University, a …

BACKGROUND: The glutamate model of schizophrenia proposes that altered glutamatergic
neurotransmission is fundamental to the development of the disorder. In addition, its …

Purpose: To evaluate the reproducibility of γ‐amino‐butyric acid (GABA) and glutamate
concentrations derived using three different spectral fitting methods, and to investigate gender‐…

It was recently observed that dehydration causes shrinkage of brain tissue and an associated
increase in ventricular volume. Negative effects of dehydration on cognitive performance …

BACKGROUND: Animal models of psychosis propose that striatal hyperdopaminergia is
driven by abnormalities in hippocampal glutamatergic neurotransmission, but this has never …

Functional neuroimaging metrics are thought to reflect changes in neurotransmitter flux, but
changes in neurotransmitter levels have not been demonstrated in humans during a …

Although posttraumatic stress disorder (PTSD) is associated with a variety of structural and
functional brain changes, the molecular pathophysiological mechanisms underlying these …

Context Alterations in glutamatergic neurotransmission and cerebral cortical dysfunction are
thought to be central to the pathophysiology of psychosis, but the relationship between …

Despite improved survival, many preterm infants undergo subsequent neurodevelopmental
impairment. To date, no neuroprotective therapies have been implemented into clinical …

Background/Aims: Stereotactic postoperative imaging is essential for verification of the
position of electrodes implanted for deep brain stimulation (DBS). MRI offers superior …