User profiles for Ryan A. Melnyk
Ryan A. MelnykBerkeley Lab Verified email at lbl.gov Cited by 2002 |
Mutant phenotypes for thousands of bacterial genes of unknown function
One-third of all protein-coding genes from bacterial genomes cannot be annotated with a
function. Here, to investigate the functions of these genes, we present genome-wide mutant …
function. Here, to investigate the functions of these genes, we present genome-wide mutant …
Surface multiheme c-type cytochromes from Thermincola potens and implications for respiratory metal reduction by Gram-positive bacteria
Almost nothing is known about the mechanisms of dissimilatory metal reduction by Gram-positive
bacteria, although they may be the dominant species in some environments. …
bacteria, although they may be the dominant species in some environments. …
[HTML][HTML] Toward a mechanistic understanding of anaerobic nitrate-dependent iron oxidation: balancing electron uptake and detoxification
The anaerobic oxidation of Fe(II) by subsurface microorganisms is an important part of
biogeochemical cycling in the environment, but the biochemical mechanisms used to couple iron …
biogeochemical cycling in the environment, but the biochemical mechanisms used to couple iron …
Convergent gain and loss of genomic islands drive lifestyle changes in plant-associated Pseudomonas
Host-associated bacteria can have both beneficial and detrimental effects on host health.
While some of the molecular mechanisms that determine these outcomes are known, little is …
While some of the molecular mechanisms that determine these outcomes are known, little is …
A Genome-Wide Screen Identifies Genes in Rhizosphere-Associated Pseudomonas Required to Evade Plant Defenses
Pseudomonas fluorescens and related plant root (“rhizosphere”)-associated species
contribute to plant health by modulating defenses and facilitating nutrient uptake. To identify …
contribute to plant health by modulating defenses and facilitating nutrient uptake. To identify …
[HTML][HTML] Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics
For many bacteria with sequenced genomes, we do not understand how they synthesize
some amino acids. This makes it challenging to reconstruct their metabolism, and has led to …
some amino acids. This makes it challenging to reconstruct their metabolism, and has led to …
Rhizosphere‐associated Pseudomonas induce systemic resistance to herbivores at the cost of susceptibility to bacterial pathogens
…, CL Wiesmann, LR Shapiro, RA Melnyk… - Molecular …, 2018 - Wiley Online Library
Plant‐associated soil microbes are important mediators of plant defence responses to diverse
above‐ground pathogen and insect challengers. For example, closely related strains of …
above‐ground pathogen and insect challengers. For example, closely related strains of …
Commensal Pseudomonas fluorescens Strains Protect Arabidopsis from Closely Related Pseudomonas Pathogens in a Colonization-Dependent Manner
NR Wang, CL Wiesmann, RA Melnyk, SS Hossain… - MBio, 2022 - Am Soc Microbiol
Plants form commensal associations with soil microorganisms, creating a root microbiome
that provides benefits, including protection against pathogens. While bacteria can inhibit …
that provides benefits, including protection against pathogens. While bacteria can inhibit …
Structure and evolution of chlorate reduction composite transposons
The genes for chlorate reduction in six bacterial strains were analyzed in order to gain insight
into the metabolism. A newly isolated chlorate-reducing bacterium ( Shewanella alga e …
into the metabolism. A newly isolated chlorate-reducing bacterium ( Shewanella alga e …
[HTML][HTML] MamO is a repurposed serine protease that promotes magnetite biomineralization through direct transition metal binding in magnetotactic bacteria
Many living organisms transform inorganic atoms into highly ordered crystalline materials.
An elegant example of such biomineralization processes is the production of nano-scale …
An elegant example of such biomineralization processes is the production of nano-scale …