Deciphering the immunopeptidome in vivo reveals new tumour antigens

…, T Fessenden, KB Nguyen, PS Winter, RE Kohn… - Nature, 2022 - nature.com
Immunosurveillance of cancer requires the presentation of peptide antigens on major
histocompatibility complex class I (MHC-I) molecules 1 , 2 , 3 , 4 – 5 . Current approaches to …

Deciphering the tumor-specific immunopeptidome in vivo with genetically engineered mouse models

…, S Naranjo, T Fessenden, PS Winter, RE Kohn… - bioRxiv, 2021 - biorxiv.org
Effective immunosurveillance of cancer requires the presentation of peptide antigens on
major histocompatibility complex Class I (MHC-I). Recent developments in proteomics have …

Carboxyamido-triazole modulates retinal pigment epithelial and choroidal endothelial cell attachment, migration, proliferation, and MMP-2 secretion of choroidal …

…, L Masiero, P Wiedemann, SJ Ryan, EC Kohn - Current eye …, 2005 - Taylor & Francis
… Felder CC, Ma AL, Liotta LA, Kohn E C. The antiproliferative and antimetastatic compound
L651582 inhibits muscarinic acetylcholine receptor-stimulated calcium influx and arachidonic …

Aripiprazole in pervasive developmental disorder not otherwise specified and Asperger's disorder: a 14-week, prospective, open-label study

KA Stigler, JT Diener, AE Kohn, L Li… - Journal of Child and …, 2009 - liebertpub.com
Objective: The aim of this study was to determine the effectiveness and tolerability of
aripiprazole for irritability in pervasive developmental disorder not otherwise specified (PDD-NOS) …

[CITATION][C] Minutes of the Council

…, DF Rentshler, M Rigby, MD Rosenberg, EF Ryan… - journals.ametsoc.org
60. Voted (11), to approve of the Secretary's sending the Chief of the Weather Bureau a letter
stating that" In the opinion of the Council of the American Meteorological Society, according …

[HTML][HTML] Activation of the DNA damage response by RNA viruses

EL Ryan, R Hollingworth, RJ Grand - Biomolecules, 2016 - mdpi.com
RNA viruses are a genetically diverse group of pathogens that are responsible for some of
the most prevalent and lethal human diseases. Numerous viruses introduce DNA damage …

[HTML][HTML] Medical, nursing, and physician assistant student knowledge and attitudes toward climate change, pollution, and resource conservation in health care

EC Ryan, R Dubrow, JD Sherman - BMC Medical Education, 2020 - Springer
Background Climate change and pollution generated by the health care sector impose
significant public health burdens. This study aimed to assess medical, nursing and physician …

GBA1-associated parkinsonism: new insights and therapeutic opportunities

E Ryan, G Seehra, P Sharma… - Current opinion in …, 2019 - journals.lww.com
As our understanding of GBA1-associated Parkinson disease increases, new treatment
opportunities emerge. MicroRNA profiles are providing examples of both up-regulated and down-…

[HTML][HTML] Preclinical evaluation of the AR inhibitor enzalutamide in triple-negative breast cancer cells

…, SF Madden, NC Synnott, EJ Ryan… - Endocrine-related …, 2016 - erc.bioscientifica.com
The androgen receptor (AR) is present in approximately 80% of invasive breast cancer
patients and in up to 30% of patients with triple-negative breast cancer (TNBC). Therefore, our …

Species-specific bacteria identification using differential mobility spectrometry and bioinformatics pattern recognition

…, MD Krebs, SJ Cohen, JE Zeskind, ET Ryan… - Analytical …, 2005 - ACS Publications
As bacteria grow and proliferate, they release a variety of volatile compounds that can be
profiled and used for speciation, providing an approach amenable to disease diagnosis …