Type IV pili ( T4P ) are bacterial virulence factors involved in a wide variety of functions
including deoxyribonucleic acid uptake, surface attachment, biofilm formation and twitching …

The opportunistic pathogen Pseudomonas aeruginosa is a leading cause of nosocomial
infections. Its relatively impermeable outer membrane ( OM ) limits antibiotic entry, and a …

FimV is a Pseudomonas aeruginosa inner membrane hub protein that modulates levels of
the second messenger, cyclic AMP (cAMP), through the activation of adenylate cyclase CyaB. …

Type IVa pili (T4aP) are ubiquitous microbial appendages used for adherence, twitching
motility, DNA uptake, and electron transfer. Many of these functions depend on dynamic …

Many bacterial pathogens, including Pseudomonas aeruginosa, use type IVa pili (T4aP) for
attachment and twitching motility. T4aP are composed primarily of major pilin subunits, …

FimV is a Pseudomonas aeruginosa inner membrane protein that regulates intracellular
cyclic AMP (cAMP) levels—and thus type IV pilus (T4P)-mediated twitching motility and type II …

Type IV pili (T4aP) are ubiquitous microbial appendages used for adherence, twitching
motility, DNA uptake, and electron transfer. Many of these functions depend on dynamic …

Background: Type IVa pilus (T4aP) assembly is primed by minor pilins. Results: Non-core
subunit PilE interacts with core minor pilins and is incorporated into pili; PilE is structurally …

Despite advances in therapy, acquired immune deficiency syndrome (AIDS) continues to be
a global problem. New therapeutic avenues are being explored, including dendritic cell (DC)…

Introduction: Epithelial ovarian cancer (EOC) remains a leading cause of gynecological
cancer-related deaths due its late diagnosis and the absence of effective treatments for chemo-…