User profiles for Ryan Samarakoon
Ryan SamarakoonVanderbilt University School of Engineering Verified email at vanderbilt.edu Cited by 183 |
Oligogenic inheritance of a human heart disease involving a genetic modifier
Complex genetic mechanisms are thought to underlie many human diseases, yet experimental
proof of this model has been elusive. Here, we show that a human cardiac anomaly can …
proof of this model has been elusive. Here, we show that a human cardiac anomaly can …
[PDF][PDF] Individual variability of neural computations in the primate retina
Variation in the neural code contributes to making each individual unique. We probed neural
code variation using ∼100 population recordings from major ganglion cell types in the …
code variation using ∼100 population recordings from major ganglion cell types in the …
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier
CA Gifford, SS Ranade, R Samarakoon, HT Salunga… - bioRxiv, 2018 - biorxiv.org
Complex genetic inheritance is thought to underlie many human diseases, yet experimental
proof of this model has been elusive. Here, we show that a human congenital heart defect, …
proof of this model has been elusive. Here, we show that a human congenital heart defect, …
[BOOK][B] Retinal Ganglion Cell Responses to Extracellular Stimulation for High-Fidelity Vision Restoration
S Madugula - 2022 - search.proquest.com
Future high-fidelity, large-scale electrical brain-machine interfaces will have the ability to
restore population-level neural function to treat debilitating sensorimotor conditions. Achieving …
restore population-level neural function to treat debilitating sensorimotor conditions. Achieving …
Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration
…, S Sarasija, JT Laboy, R Samarakoon… - Aging …, 2021 - Wiley Online Library
Metabolic dysfunction and protein aggregation are common characteristics that occur in age‐related
neurodegenerative disease. However, the mechanisms underlying these …
neurodegenerative disease. However, the mechanisms underlying these …
A Formal [4 + 4] Complementary Ambiphile Pairing Reaction: A New Cyclization Pathway for ortho-Quinone Methides
TB Samarakoon, MY Hur, RD Kurtz, PR Hanson - Organic letters, 2010 - ACS Publications
A formal, one-pot [4 + 4] cyclization pathway for the generation of eight-membered sultams
via in situ generation of an ortho -quinone methide ( o -QM) is reported. The pairing of …
via in situ generation of an ortho -quinone methide ( o -QM) is reported. The pairing of …
Divergence time calibrations for ancient lineages of Ascomycota classification based on a modern review of estimations
MC Samarakoon, KD Hyde, S Hongsanan… - Fungal Diversity, 2019 - Springer
Inaccurate taxonomic placement of fossils can lead to the accumulation of errors in molecular
clock studies and their generated evolutionary lineages. There are limited fossil data that …
clock studies and their generated evolutionary lineages. There are limited fossil data that …
Aging, memory, and nonhierarchical energy landscape of spin jam
A Samarakoon, TJ Sato, T Chen… - Proceedings of the …, 2016 - National Acad Sciences
The notion of complex energy landscape underpins the intriguing dynamical behaviors in
many complex systems ranging from polymers, to brain activity, to social networks and glass …
many complex systems ranging from polymers, to brain activity, to social networks and glass …
[HTML][HTML] Rac-GTPase promotes fibrotic TGF-β1 signaling and chronic kidney disease via EGFR, p53, and Hippo/YAP/TAZ pathways
… Samarakoon performed the experiments; all authors were involved in data analysis; R. …
Samarakoon and PJ Higgins edited the manuscript; and all authors agreed on the …
Samarakoon and PJ Higgins edited the manuscript; and all authors agreed on the …
Penicillin allergy delabeling: opportunities for implementation and dissemination
U Samarakoon, J Accarino, AG Wurcel… - Annals of Allergy …, 2023 - Elsevier
Although existing as a safety measure to prevent iatrogenic harm, unconfirmed penicillin
allergy labels have a negative impact on personal and public health. One downstream effect of …
allergy labels have a negative impact on personal and public health. One downstream effect of …