Senescence is a state of proliferative arrest which has been described as a protective
mechanism against the malignant transformation of cells. However, senescent cells have also …

A hallmark of senescence is the acquisition of an enhanced secretome comprising
inflammatory mediators and tissue remodelling agents – the senescence‐associated secretory …

Senescence, a state of stable growth arrest, plays an important role in ageing and age‐related
diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence …

Senescence is a widely appreciated tumour suppressive mechanism, which acts as a barrier
to cancer development by arresting cell cycle progression in response to harmful stimuli. …

Senescence occurs in response to a number of damaging stimuli to limit oncogenic
transformation and cancer development. As no single, universal senescence marker has been …

This study investigated the relative contribution of psychiatric symptoms and psychotropic
medications on the sleep-wake cycle. Actigraphy and clinical assessments (Brief Psychiatric …

Killing senescent cells to improve health-span holds great promise. However, screening for
senescence-regulating genes and molecules is challenging because these cells do not …

Respiratory oscillometry (or forced oscillation technique (FOT)), measures the mechanical
properties of the respiratory system by superimposing oscillatory pressure waves at the mouth …

Senescence classification is an acknowledged challenge within the field, as markers are cell-type
and context dependent. Currently, multiple morphological and immunofluorescence …

Senescence classification is an acknowledged challenge within the field, as markers are cell-type
and context dependent. Currently, multiple morphological and immunofluorescence …