[HTML][HTML] Machine learning approaches to TCR repertoire analysis

Y Katayama, R Yokota, T Akiyama… - Frontiers in …, 2022 - frontiersin.org
Sparked by the development of genome sequencing technology, the quantity and quality of
data handled in immunological research have been changing dramatically. Various data and …

[HTML][HTML] Detecting causality by combined use of multiple methods: Climate and brain examples

Y Hirata, JM Amigó, Y Matsuzaka, R Yokota… - PloS one, 2016 - journals.plos.org
Identifying causal relations from time series is the first step to understanding the behavior of
complex systems. Although many methods have been proposed, few papers have applied …

Geographical profiling incorporating neighbourhood‐level factors using spatial interaction modelling

K Hirama, K Yokota, Y Otsuka… - Journal of …, 2023 - Wiley Online Library
The aim of this study was to examine the applicability of methods that use spatial interaction
modelling to predict the most probable area for an offender's residence. Tokyo, which is the …

Evaluation of CRISPR diversity in the human skin microbiome for personal identification

K Toyomane, R Yokota, K Watanabe, T Akutsu… - Msystems, 2021 - Am Soc Microbiol
The highly personalized human skin microbiome may serve as a viable marker in personal
identification. Amplicon sequencing resolution using 16S rRNA cannot identify bacterial …

[HTML][HTML] Quantification of inter-sample differences in T-cell receptor repertoires using sequence-based information

R Yokota, Y Kaminaga, TJ Kobayashi - Frontiers in immunology, 2017 - frontiersin.org
Inter-sample comparisons of T-cell receptor (TCR) repertoires are crucial for gaining a better
understanding of the immunological states determined by different collections of T cells …

[HTML][HTML] Response variance in functional maps: neural Darwinism revisited

H Takahashi, R Yokota, R Kanzaki - PLoS One, 2013 - journals.plos.org
The mechanisms by which functional maps and map plasticity contribute to cortical computation
remain controversial. Recent studies have revisited the theory of neural Darwinism to …

N-terminal α-ketoamide peptides: formation and transamination

SH Lee, H Kyung, R Yokota, T Goto… - Chemical Research in …, 2014 - ACS Publications
We have previously reported that N-terminal α-ketoamide peptides can be formed through 4-oxo-2(E)-nonenal
(ONE)-derived oxidative decarboxylation of aspartic acid (Asp), which …

Flying object detection system using an omnidirectional camera

M Hirabayashi, K Kurosawa, R Yokota, D Imoto… - Forensic Science …, 2020 - Elsevier
While the effective utilization of drones is expected to grow in a wide range of fields, there
are concerns over new threats related to the exploitation of drones that have not been …

Experimental and theoretical bases for mechanisms of antigen discrimination by T cells

MK Kajita, R Yokota, K Aihara, TJ Kobayashi - Biophysics, 2015 - jstage.jst.go.jp
Interaction only within specific molecules is a requisite for accurate operations of a biochemical
reaction in a cell where bulk of background molecules exist. While structural specificity is …

[HTML][HTML] Optimization of microbial DNA extraction from human skin samples for CRISPR typing

K Toyomane, R Yokota, K Watanabe, T Akutsu… - Forensic Science …, 2022 - Elsevier
The human skin microbiome, a complex microbial community harbored by the human skin
surface, has been proposed as a new forensic genetic marker for human identification to …