User profiles for S Austin Hammond
S. Austin HammondOPAL Platform Lead, Global Institute for Food Security Verified email at gifs.ca Cited by 1259 |
ABySS 2.0: resource-efficient assembly of large genomes using a Bloom filter
The assembly of DNA sequences de novo is fundamental to genomics research. It is the first
of many steps toward elucidating and characterizing whole genomes. Downstream …
of many steps toward elucidating and characterizing whole genomes. Downstream …
[HTML][HTML] AMPlify: attentive deep learning model for discovery of novel antimicrobial peptides effective against WHO priority pathogens
Background Antibiotic resistance is a growing global health concern prompting researchers
to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting …
to seek alternatives to conventional antibiotics. Antimicrobial peptides (AMPs) are attracting …
[HTML][HTML] The North American bullfrog draft genome provides insight into hormonal regulation of long noncoding RNA
SA Hammond, RL Warren, BP Vandervalk… - Nature …, 2017 - nature.com
Frogs play important ecological roles, and several species are important model organisms
for scientific research. The globally distributed Ranidae (true frogs) are the largest frog family, …
for scientific research. The globally distributed Ranidae (true frogs) are the largest frog family, …
Spruce giga‐genomes: structurally similar yet distinctive with differentially expanding gene families and rapidly evolving genes
…, D Cheng, P Plettner, SA Hammond… - The Plant …, 2022 - Wiley Online Library
Spruces (Picea spp.) are coniferous trees widespread in boreal and mountainous forests of
the northern hemisphere, with large economic significance and enormous contributions to …
the northern hemisphere, with large economic significance and enormous contributions to …
[HTML][HTML] The Genome of the Beluga Whale (Delphinapterus leucas)
…, S Chan, RL Warren, SA Hammond, S Bilobram… - Genes, 2017 - mdpi.com
The beluga whale is a cetacean that inhabits arctic and subarctic regions, and is the only
living member of the genus Delphinapterus. The genome of the beluga whale was determined …
living member of the genus Delphinapterus. The genome of the beluga whale was determined …
Knock-down of heterogeneous nuclear ribonucleoprotein A1 results in neurite damage, altered stress granule biology, and cellular toxicity in differentiated neuronal …
…, HE Salapa, PA Thibault, C Hutchinson, SA Hammond… - eneuro, 2021 - eneuro.org
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) is an RNA binding protein (RBP)
that is localized within neurons and plays crucial roles in RNA metabolism. Its importance in …
that is localized within neurons and plays crucial roles in RNA metabolism. Its importance in …
[HTML][HTML] Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel
R Plett, P Mellor, S Kendall, SA Hammond, A Boulet… - Scientific Reports, 2022 - nature.com
The lack of targeted therapies for triple-negative breast cancer (TNBC) contributes to their
high mortality rates and high risk of relapse compared to other subtypes of breast cancer. Most …
high mortality rates and high risk of relapse compared to other subtypes of breast cancer. Most …
[HTML][HTML] De novo Transcriptome Assemblies of Rana (Lithobates) catesbeiana and Xenopus laevis Tadpole Livers for Comparative Genomics without Reference …
In this work we studied the liver transcriptomes of two frog species, the American bullfrog (Rana
(Lithobates) catesbeiana) and the African clawed frog (Xenopus laevis). We used high …
(Lithobates) catesbeiana) and the African clawed frog (Xenopus laevis). We used high …
[HTML][HTML] Autoimmunity to a ribonucleoprotein drives neuron loss in multiple sclerosis models
…, TE Stang, PA Thibault, SA Hammond… - Neurobiology of …, 2022 - Elsevier
Neurodegeneration, the progressive loss or damage to neurons and axons, underlies
permanent disability in multiple sclerosis (MS); yet its mechanisms are incompletely understood. …
permanent disability in multiple sclerosis (MS); yet its mechanisms are incompletely understood. …
[HTML][HTML] hnRNP A1 dysfunction alters RNA splicing and drives neurodegeneration in multiple sclerosis (MS)
…, HM Abidullah, S Austin Hammond… - Nature …, 2024 - nature.com
Neurodegeneration is the primary driver of disease progression in multiple sclerosis (MS)
resulting in permanent disability, creating an urgent need to discover its underlying …
resulting in permanent disability, creating an urgent need to discover its underlying …