User profiles for S Brunak

Søren Brunak

Professor of Disease Systems Biology, University of Copenhagen
Verified email at cpr.ku.dk
Cited by 145285

Prediction of post‐translational glycosylation and phosphorylation of proteins from the amino acid sequence

…, R Gupta, S Gammeltoft, S Brunak - …, 2004 - Wiley Online Library
… He also works part-time for the Danish biotech company NsGene A/S coordinating the
bioinformatics part of the company’s gene discovery programme. He teaches Gene Finding and …

Assessing the accuracy of prediction algorithms for classification: an overview

P Baldi, S Brunak, Y Chauvin, CAF Andersen… - …, 2000 - academic.oup.com
… and Brunak,S. (1996) Splice site prediction in Arabidopsis thaliana pre-mRNA by combining
local … and Brunak,S. (1996) Defining a similarity threshold for a functional protein sequence …

Mining electronic health records: towards better research applications and clinical care

PB Jensen, LJ Jensen, S Brunak - Nature Reviews Genetics, 2012 - nature.com
Clinical data describing the phenotypes and treatment of patients represents an underused
data source that has much greater research potential than is currently realized. Mining of …

[HTML][HTML] A human gut microbial gene catalogue established by metagenomic sequencing

…, Y Li, X Zhang, S Li, N Qin, H Yang, J Wang, S Brunak… - nature, 2010 - nature.com
To understand the impact of gut microbes on human health and well-being it is crucial to
assess their genetic potential. Here we describe the Illumina-based metagenomic sequencing, …

Enterotypes of the human gut microbiome

…, F Guarner, O Pedersen, WM De Vos, S Brunak… - nature, 2011 - nature.com
Our knowledge of species and functional composition of the human gut microbiome is rapidly
increasing, but it is still based on very few cohorts and little is known about variation across …

Richness of human gut microbiome correlates with metabolic markers

…, S Sunagawa, J Tap, S Tims, EG Zoetendal, S Brunak… - Nature, 2013 - nature.com
We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we
report the human gut microbial composition in a population sample of 123 non-obese and 169 …

[HTML][HTML] SignalP 6.0 predicts all five types of signal peptides using protein language models

…, SI Pihl, KD Tsirigos, O Winther, S Brunak… - Nature …, 2022 - nature.com
… credit to the original author(s) and the source, provide a … ’s Creative Commons license,
unless indicated otherwise in a credit line to the material. If material is not included in the article’s

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

N Blom, S Gammeltoft, S Brunak - Journal of molecular biology, 1999 - Elsevier
… The ability of the serine and threonine networks to recognize a larger fraction of each other’s
sites than of tyrosine sites is consistent with the known specificity overlap of threonine and …

[HTML][HTML] Mapping the human genetic architecture of COVID-19

…, S Ciesek, S Bombace, S Wilfling, S Brunak… - Nature, 2021 - nature.com
The genetic make-up of an individual contributes to the susceptibility and response to viral
infection. Although environmental, clinical and social factors have a role in the chance of …

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites.

H Nielsen, J Engelbrecht, S Brunak… - Protein …, 1997 - academic.oup.com
… The best measure was the geometric average of the C-score Based on the numbers of
correctly and incorrectly predicted and a smoothed derivative of the S-score, termed the Y-score: …