… SK Burley is a postdoctoral feliow and GA Petsko is an associate professor in the Department
of Chemistry, … Wang and SK Burley, in preparation (structure of benzoyl ester of L-Phe). …

… TBP’s unusual mode of DNA binding and recognition may also explain the profound toxicity
of minor groove-binding anti-tumor agents, such as netropsin and distamycin A. Both of …

Publisher Summary This chapter reviews the subject of noncovalent interactions in proteins
with particular emphasis on the so-called weakly polar interactions. The chapter discusses …

The gene product of the ob locus is important in the regulation of body weight. The ob product
was shown to be present as a 16-kilodalton protein in mouse and human plasma but was …

… as human pathogens, thereby facilitating discovery and development of new treatments
and vaccines to contain the current pandemic and manage other coronavirus outbreak(s) that …

Large biomolecular structures are being determined experimentally on a daily basis using
established techniques such as crystallography and electron microscopy. In addition, …

… They must be based on actual experimental measurements on sample specimens of the
biological macromolecule(s) comprising the structure. For full details, see wwpdb.org.) …

… We thank S. Jacques for help with protein production, B. Chait and S. Cohen for the mass
spectrometry at the National Resource for Mass Spectrometric Analysis of Biological …

… visualization is fundamental to interrogating 3D macromolecular structures in order to gain
an atomic level understanding of biological processes or to explore the mechanism(s) of drug …

… Formation of the wwPDB has ensured that researchers, educators and students around the
world enjoy open access to the world’s structure data following these guidelines. Formation …