… stroke; all types of dementia versus Alzheimer’s disease, vascular dementia, mixed vascular
and Alzheimer’s dementia; and neuropsychological measurements used to assess …

Cervical-artery dissection (CAD) is a major cause of cerebral ischaemia in young adults and
can lead to various clinical symptoms, some of which are benign (eg, headache, neck pain, …

Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …

Abstract Characterization of the genetic landscape of Alzheimer’s disease (AD) and related
dementias (ADD) provides a unique opportunity for a better understanding of the associated …

Context Genome-wide association studies (GWAS) have recently identified CLU, PICALM,
and CR1 as novel genes for late-onset Alzheimer disease (AD). Objectives To identify and …

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease.
We report the largest genetic association study of blood pressure traits (systolic, diastolic …

… Debette was supported by a Fulbright grant and received an award from the Bettencourt-…
Debette reports no disclosures. Dr. Seshadri serves as an Associate Editor for the Journal of …

Background The genes underlying the risk of stroke in the general population remain
undetermined. Methods We carried out an analysis of genomewide association data generated …

Background and Purpose— White matter hyperintensities and MRI-defined brain infarcts (BIs)
have individually been related to stroke, dementia, and mortality in population-based …

Objective: Higher dietary intake and circulating levels of docosahexaenoic acid (DHA) and
eicosapentaenoic acid (EPA) have been related to a reduced risk for dementia, but the …