User profiles for Sébastien Wielgoss

Sébastien Wielgoss

Senior Scientist, ETH Zürich, Institute of Integrative Biology, Lab for Evolutionary Biology
Verified email at env.ethz.ch
Cited by 1603

Tempo and mode of genome evolution in a 50,000-generation experiment

…, JL Blanchard, A Dasgupta, GC Wu, S Wielgoss… - Nature, 2016 - nature.com
Adaptation by natural selection depends on the rates, effects and interactions of many
mutations, making it difficult to determine what proportion of mutations in an evolving lineage are …

Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

S Wielgoss, JE Barrick, O Tenaillon… - Proceedings of the …, 2013 - National Acad Sciences
Mutations are the ultimate source of heritable variation for evolution. Understanding how
mutation rates themselves evolve is thus essential for quantitatively understanding many …

Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli

S Wielgoss, JE Barrick, O Tenaillon… - G3: Genes …, 2011 - academic.oup.com
The quantification of spontaneous mutation rates is crucial for a mechanistic understanding
of the evolutionary process. In bacteria, traditional estimates using experimental or …

[HTML][HTML] Bacterial predator-prey coevolution accelerates genome evolution and selects on virulence-associated prey defences

RR Nair, M Vasse, S Wielgoss, L Sun, YTN Yu… - Nature …, 2019 - nature.com
Generalist bacterial predators are likely to strongly shape many important ecological and
evolutionary features of microbial communities, for example by altering the character and pace …

Rapid and widespread de novo evolution of kin discrimination

…, I Dinkelacker, M Amherd, S Wielgoss… - Proceedings of the …, 2015 - National Acad Sciences
Diverse forms of kin discrimination, broadly defined as alteration of social behavior as a
function of genetic relatedness among interactants, are common among social organisms from …

Population structure of the parasitic nematode Anguillicola crassus, an invader of declining North Atlantic eel stocks

S Wielgoss, H Taraschewski, A Meyer… - Molecular ecology, 2008 - Wiley Online Library
Probably half of all animal species exhibit a parasitic lifestyle and numerous parasites have
recently expanded their distribution and host ranges due to anthropogenic activities. Here, …

A barrier to homologous recombination between sympatric strains of the cooperative soil bacterium Myxococcus xanthus

S Wielgoss, X Didelot, RR Chaudhuri, X Liu… - The ISME …, 2016 - academic.oup.com
The bacterium Myxococcus xanthus glides through soil in search of prey microbes, but when
food sources run out, cells cooperatively construct and sporulate within multicellular fruiting …

[HTML][HTML] Bacteriophages of Myxococcus xanthus, a Social Bacterium

M Vasse, S Wielgoss - Viruses, 2018 - mdpi.com
Bacteriophages have been used as molecular tools in fundamental biology investigations for
decades. Beyond this, however, they play a crucial role in the eco-evolutionary dynamics of …

Social genes are selection hotspots in kin groups of a soil microbe

S Wielgoss, R Wolfensberger, L Sun, F Fiegna… - Science, 2019 - science.org
The composition of cooperative systems, including animal societies, organismal bodies, and
microbial groups, reflects their past and shapes their future evolution. However, genomic …

[PDF][PDF] On the origin of Anguillicoloides crassus, the invasive nematode of anguillid eels.

F Lefebvre, S Wielgoss, K Nagasawa… - Aquatic …, 2012 - researchgate.net
The nematode Anguillicoloides crassus is one of the many threats hanging over anguillid
eels, now known to infect six Anguilla species worldwide. It was first described in Japan, in …