[HTML][HTML] Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation

…, T Müller, Y Zheng, S Schubert… - The Journal of …, 2016 - Am Soc Clin Investig
Successful bacterial pathogens produce an array of virulence factors that allow subversion
of the immune system and persistence within the host. For example, uropathogenic …

MALDI-TOF MS in microbiological diagnostics—identification of microorganisms and beyond (mini review)

A Wieser, L Schneider, J Jung, S Schubert - Applied microbiology and …, 2012 - Springer
Few developments in microbiological diagnostics have had such a rapid impact on species
level identification of microorganisms as matrix-assisted laser desorption/ionization time of …

[HTML][HTML] Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain–containing proteins

C Cirl, A Wieser, M Yadav, S Duerr, S Schubert… - Nature medicine, 2008 - nature.com
Pathogenic microbes have evolved sophisticated molecular strategies to subvert host
defenses. Here we show that virulent bacteria interfere directly with Toll-like receptor (TLR) …

Matrix-assisted laser desorption ionization–time of flight mass spectrometry-based functional assay for rapid detection of resistance against β-lactam antibiotics

K Sparbier, S Schubert, U Weller… - Journal of clinical …, 2012 - Am Soc Microbiol
Resistance against β-lactam antibiotics is a growing challenge for managing severe bacterial
infections. The rapid and cost-efficient determination of β-lactam resistance is an important …

Bacteroides vulgatus protects against Escherichia coli-induced colitis in gnotobiotic interleukin-2-deficient mice

M Waidmann, O Bechtold, J Frick, H Lehr, S Schubert… - Gastroenterology, 2003 - Elsevier
BACKGROUND & AIMS:: The microflora plays a crucial role in inflammatory bowel diseases
(IBDs). Specific pathogen-free (SPF), but not germ-free, interleukin (IL)-2-deficient (IL-2−/−) …

[HTML][HTML] Ultra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome

…, NA Kulak, G Pichler, PE Geyer, J Jung, S Schubert… - Genome medicine, 2016 - Springer
Background The oral cavity is home to one of the most diverse microbial communities of the
human body and a major entry portal for pathogens. Its homeostasis is maintained by saliva, …

[HTML][HTML] Novel, improved sample preparation for rapid, direct identification from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight …

S Schubert, K Weinert, C Wagner, B Gunzl… - The Journal of Molecular …, 2011 - Elsevier
Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS)
is widely used for rapid and reliable identification of bacteria and yeast grown on agar …

Label-free in situ discrimination of live and dead bacteria by surface-enhanced Raman scattering

…, D Yang, NP Ivleva, NE Mircescu, S Schubert… - Analytical …, 2015 - ACS Publications
Techniques to distinguish between live and dead bacteria in a quantitative manner are in
high demand in numerous fields including medical care, food safety, and public security as …

Yersinia High-Pathogenicity Island Contributes to Virulence in Escherichia coli Causing Extraintestinal Infections

S Schubert, B Picard, S Gouriou… - Infection and …, 2002 - Am Soc Microbiol
The Yersinia high-pathogenicity island (HPI) encodes an iron uptake system mediated by
the siderophore yersiniabactin (Ybt) and confers the virulence of highly pathogenic Yersinia …

Quantitative matrix-assisted laser desorption ionization–time of flight mass spectrometry for rapid resistance detection

C Lange, S Schubert, J Jung… - Journal of clinical …, 2014 - Am Soc Microbiol
Antibiotic resistance in Gram-negative microorganisms is an increasing health care problem.
The rapid detection of such resistance is crucial for starting an early specific therapy and to …