Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future …

…, P Roth, M Sanson, D Schiff, SC Short… - Neuro …, 2020 - academic.oup.com
Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Low-dose hypersensitivity: current status and possible mechanisms

MC Joiner, B Marples, P Lambin, SC Short… - International Journal of …, 2001 - Elsevier
… This last parameter is a quantitative measure of the excretion response to carbachol,
administered sc at the moment that the uptake reaches a plateau. Registration of dosimetric CT and …

Systematic review of synthetic computed tomography generation methodologies for use in magnetic resonance imaging–only radiation therapy

E Johnstone, JJ Wyatt, AM Henry, SC Short… - International Journal of …, 2018 - Elsevier
… assignments, atlas-based techniques, and voxel-based techniques, with the latter being
subdivided into techniques using standard MRI sequences alone and those using ultra-short

[PDF][PDF] Glioma progression is shaped by genetic evolution and microenvironment interactions

…, G Rao, G Reifenberger, N Sanai, SC Short… - Cell, 2022 - cell.com
The factors driving therapy resistance in diffuse glioma remain poorly understood. To
identify treatment-associated cellular and genetic changes, we analyzed RNA and/or DNA …

ESTRO-ACROP guideline “target delineation of glioblastomas”

…, G Minniti, RO Mirimanoff, U Ricardi, SC Short… - Radiotherapy and …, 2016 - Elsevier
… While for the majority of patients treated with short courses of palliative radiotherapy 3D-CRT
is likely to be adequate, there is growing realisation that prolonged survival can be …

Longitudinal molecular trajectories of diffuse glioma in adults

…, JK Sa, M Schuster, BL Shaw, SC Short… - Nature, 2019 - nature.com
The evolutionary processes that drive universal therapeutic resistance in adult patients with
diffuse glioma remain unclear 1 , 2 . Here we analysed temporally separated DNA-…

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade

…, RG Vile, SD Griffin, LF Stead, SC Short… - Science translational …, 2018 - science.org
Immune checkpoint inhibitors, including those targeting programmed cell death protein 1 (PD-1),
are reshaping cancer therapeutic strategies. Evidence suggests, however, that tumor …

ATR-dependent radiation-induced γH2AX foci in bystander primary human astrocytes and glioma cells

S Burdak-Rothkamm, SC Short, M Folkard… - Oncogene, 2007 - nature.com
Radiotherapy is an important treatment for patients suffering from high-grade malignant
gliomas. Non-targeted (bystander) effects may influence these cells' response to radiation and …

Effects of cell cycle phase on low-dose hyper-radiosensitivity

SC Short, M Woodcock, B Marples… - International journal of …, 2003 - Taylor & Francis
Purpose : To examine the low-dose radiation response of human glioma cell lines separated
into different cell-cycle phases and to determine if low-dose hyper-radiosensitivity (HRS) …

Rad51 inhibition is an effective means of targeting DNA repair in glioma models and CD133+ tumor-derived cells

SC Short, S Giampieri, M Worku… - Neuro …, 2011 - academic.oup.com
… In knockdown experiments, cell numbers were calculated using serial dilution and were
treated on day 0 with either short-interfering RNA (siRNA) targeting Rad51 or nonspecific …