The EDS1–PAD4–ADR1 node mediates Arabidopsis pattern-triggered immunity

…, C Hua, K Fröhlich, WL Wan, M Hu, S Rao, SC Stolze… - Nature, 2021 - nature.com
Plants deploy cell-surface and intracellular leucine rich-repeat domain (LRR) immune receptors
to detect pathogens 1 . LRR receptor kinases and LRR receptor proteins at the plasma …

Grafting systems for plant cadmium research: Insights for basic plant physiology and applied mitigation

DN Marques, C Mason, SC Stolze, A Harzen… - Science of The Total …, 2023 - Elsevier
Cadmium (Cd) is a highly toxic and carcinogenic pollutant that poses a threat to human and
animal health by affecting several major organ systems. Urbanization and human activities …

[HTML][HTML] Pathogen effector recognition-dependent association of NRG1 with EDS1 and SAG101 in TNL receptor immunity

X Sun, D Lapin, JM Feehan, SC Stolze… - Nature …, 2021 - nature.com
Plants utilise intracellular nucleotide-binding, leucine-rich repeat (NLR) immune receptors
to detect pathogen effectors and activate local and systemic defence. NRG1 and ADR1 “helper…

[HTML][HTML] Coordination of microbe–host homeostasis by crosstalk with plant innate immunity

…, A Emonet, N Geldner, R Guan, SC Stolze… - Nature Plants, 2021 - nature.com
Plants grown in natural soil are colonized by phylogenetically structured communities of
microbes known as the microbiota. Individual microbes can activate microbe-associated …

CRK2 and C-terminal phosphorylation of NADPH oxidase RBOHD regulate reactive oxygen species production in Arabidopsis

…, M Citterico, A Vaattovaara, A Rokka, SC Stolze… - The Plant …, 2020 - academic.oup.com
Reactive oxygen species (ROS) are important messengers in eukaryotic organisms, and their
production is tightly controlled. Active extracellular ROS production by NADPH oxidases in …

[HTML][HTML] Carfilzomib resistance due to ABCB1/MDR1 overexpression is overcome by nelfinavir and lopinavir in multiple myeloma

A Besse, SC Stolze, L Rasche, N Weinhold, GJ Morgan… - Leukemia, 2018 - nature.com
Proteasome inhibitor (PI) carfilzomib (CFZ) has activity superior to bortezomib (BTZ) and is
increasingly incorporated in multiple myeloma (MM) frontline therapy and relapsed settings. …

Selective Photoaffinity Probe That Enables Assessment of Cannabinoid CB2 Receptor Expression and Ligand Engagement in Human Cells

M Soethoudt, SC Stolze, MV Westphal… - Journal of the …, 2018 - ACS Publications
Chemical tools and methods that report on G protein-coupled receptor (GPCR) expression
levels and receptor occupancy by small molecules are highly desirable. We report the …

Multidimensional gene regulatory landscape of a bacterial pathogen in plants

T Nobori, Y Wang, J Wu, SC Stolze, Y Tsuda… - Nature Plants, 2020 - nature.com
Understanding the gene regulation of plant pathogens is crucial for pest control and thus
global food security. An integrated understanding of bacterial gene regulation in the host is …

[PDF][PDF] Conserved biochemical defenses underpin host responses to oomycete infection in an early-divergent land plant lineage

P Carella, A Gogleva, DJ Hoey, AJ Bridgen, SC Stolze… - Current Biology, 2019 - cell.com
The expansion of plants onto land necessitated the evolution of robust defense strategies to
protect against a wide array of microbial invaders. Whereas host responses to microbial …

Cavity surface residues of PAD4 and SAG101 contribute to EDS1 dimer signaling specificity in plant immunity

…, DD Bhandari, E Penner, D Lapin, SC Stolze… - The Plant …, 2022 - Wiley Online Library
Arabidopsis pathogen effector‐triggered immunity (ETI) is controlled by a family of three
lipase‐like proteins (EDS1, PAD4, and SAG101) and two subfamilies of HET‐S/LOB‐B (HeLo)‐…