HEMOGLOBIN METABOLISM IN THE MALARIA PARASITE PLASMODIUM FALCIPARUM
SE Francis, DJ Sullivan Jr… - Annual Reviews in …, 1997 - annualreviews.org
▪ Abstract Hemoglobin degradation in intraerythrocytic malaria parasites is a vast process
that occurs in an acidic digestive vacuole. Proteases that participate in this catabolic pathway …
that occurs in an acidic digestive vacuole. Proteases that participate in this catabolic pathway …
Evidence base update: 50 years of research on treatment for child and adolescent anxiety
CK Higa-McMillan, SE Francis… - Journal of Clinical …, 2016 - Taylor & Francis
Anxiety disorders are the most common mental health disorder among children and adolescents.
We examined 111 treatment outcome studies testing 204 treatment conditions for child …
We examined 111 treatment outcome studies testing 204 treatment conditions for child …
Assessment of symptoms of DSM-IV anxiety and depression in children: A revised child anxiety and depression scale
…, L Yim, C Moffitt, LA Umemoto, SE Francis - Behaviour research and …, 2000 - Elsevier
The practical significance of assessing disorders of emotion in children is well documented,
yet few scales exist that possess conceptual if not empirical relevance to dimensions of DSM …
yet few scales exist that possess conceptual if not empirical relevance to dimensions of DSM …
Microbubble-enhanced ultrasound for vascular gene delivery
A Lawrie, AF Brisken, SE Francis, DC Cumberland… - Gene therapy, 2000 - nature.com
Progress in cardiovascular gene therapy has been hampered by concerns over the safety
and practicality of viral vectors and the inefficiency of current nonviral transfection techniques. …
and practicality of viral vectors and the inefficiency of current nonviral transfection techniques. …
Interleukin-1β in coronary arteries of patients with ischemic heart disease
…, P Gadsdon, H Holden, SE Francis… - … , and vascular biology, 1996 - Am Heart Assoc
Interleukin-1β (IL-1β ) is known to have a number of effects on the different cell types present
within coronary arteries. In this study we identified the location and phenotype of cells …
within coronary arteries. In this study we identified the location and phenotype of cells …
[PDF][PDF] Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.
IY Gluzman, SE Francis, A Oksman… - The Journal of …, 1994 - Am Soc Clin Investig
The human malaria parasite, Plasmodium falciparum, degrades nearly all its host cell
hemoglobin during a short segment of its intraerythrocytic development. This massive catabolic …
hemoglobin during a short segment of its intraerythrocytic development. This massive catabolic …
Central Roles of α5β1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies
SE Francis, KL Goh, K Hodivala-Dilke… - … , and vascular biology, 2002 - Am Heart Assoc
Vascular development and maturation are dependent on the interactions of endothelial cell
integrins with surrounding extracellular matrix. Previous investigations of the primacy of …
integrins with surrounding extracellular matrix. Previous investigations of the primacy of …
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
…, KE Luker, IY Gluzman, SE Francis… - Proceedings of the …, 1996 - National Acad Sciences
Plasmodium falciparum is the major causative agent of malaria, a disease of worldwide
importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an …
importance. Resistance to current drugs such as chloroquine and mefloquine is spreading at an …
Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.
SE Francis, IY Gluzman, A Oksman… - The EMBO …, 1994 - embopress.org
Intraerythrocytic malaria parasites rapidly degrade virtually all of the host cell hemoglobin.
We have cloned the gene for an aspartic hemoglobinase that initiates the hemoglobin …
We have cloned the gene for an aspartic hemoglobinase that initiates the hemoglobin …
Interleukin-1 receptor antagonist gene polymorphism and coronary artery disease
Background—Cytokine gene variations are contributory factors in inflammatory pathology.
Allele frequencies of interleukin (IL)-1 cluster genes [IL-1A(-889), IL-1B(-511), IL-1B(+3953), IL…
Allele frequencies of interleukin (IL)-1 cluster genes [IL-1A(-889), IL-1B(-511), IL-1B(+3953), IL…