User profiles for S. E. Hemby
Scott E. Hemby, PhDHigh Point University, Fred Wilson School of Pharmacy Verified email at highpoint.edu Cited by 8037 |
Gene expression elucidates functional impact of polygenic risk for schizophrenia
Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from dorsolateral …
confer liability is uncertain. The CommonMind Consortium sequenced RNA from dorsolateral …
Proteomics for protein expression profiling in neuroscience
WM Freeman, SE Hemby - Neurochemical research, 2004 - Springer
As the technology of proteomics moves from a theoretical approach to a practical reality,
neuroscientists will have to determine the most appropriate applications for this technology. …
neuroscientists will have to determine the most appropriate applications for this technology. …
Expression profile of transcripts in Alzheimer's disease tangle‐bearing CA1 neurons
… 2,672) by consensus sequence homology queries to known human transcripts in DOTS for
the ESTs spotted on the GDA arrays as described previously. Thus, an individual transcript …
the ESTs spotted on the GDA arrays as described previously. Thus, an individual transcript …
Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the …
Studies indicate that nucleus accumbens (NAcc) dopamine neurotransmission is involved
in the reinforcing and direct effects of cocaine. The present study was initiated to explore …
in the reinforcing and direct effects of cocaine. The present study was initiated to explore …
Two-dimensional fluorescence difference gel electrophoresis for comparative proteomics profiling
NS Tannu, SE Hemby - Nature protocols, 2006 - nature.com
Quantitative proteomics is the workhorse of the modern proteomics initiative. The gel-based
and MuDPIT approaches have facilitated vital advances in the measurement of protein …
and MuDPIT approaches have facilitated vital advances in the measurement of protein …
Gene expression profile for schizophrenia: discrete neuron transcription patterns in the entorhinal cortex
SE Hemby, SD Ginsberg, B Brunk… - Archives of General …, 2002 - jamanetwork.com
Background Several lines of evidence indicate the altered function of the temporal lobe,
including the hippocampus and entorhinal cortex (EC), is associated with schizophrenia. We …
including the hippocampus and entorhinal cortex (EC), is associated with schizophrenia. We …
Abuse liability and therapeutic potential of the Mitragyna speciosa (kratom) alkaloids mitragynine and 7‐hydroxymitragynine
… , biak biak), a plant indigenous to Southeast Asia, has emerged as a public health concern
in … work productivity amongst farm populations in Southeast Asia. Kratom leaves are chewed …
in … work productivity amongst farm populations in Southeast Asia. Kratom leaves are chewed …
Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders
…, JH Eberwine, JQ Trojanowski, SE Hemby… - Neurochemical …, 2004 - Springer
Technical and experimental advances in microaspiration techniques, RNA amplification,
quantitative real-time polymerase chain reaction (qPCR), and cDNA microarray analysis have …
quantitative real-time polymerase chain reaction (qPCR), and cDNA microarray analysis have …
Chronic stress attenuates GABAergic inhibition and alters gene expression of parvocellular neurons in rat hypothalamus
… It seems unlikely that the higher level of circulating corticosterone at the moment of the
experiment per se (control, 1.6 µg/dL; chronic stress, 4.5 µg/dL) can account for the low mIPSC …
experiment per se (control, 1.6 µg/dL; chronic stress, 4.5 µg/dL) can account for the low mIPSC …
[HTML][HTML] Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions
The safety and efficacy of kratom (Mitragyna speciosa) for treatment of pain is highly
controversial. Kratom produces more than 40 structurally related alkaloids, but most studies have …
controversial. Kratom produces more than 40 structurally related alkaloids, but most studies have …