Post-translational modifications (PTMs) are known to be essential mechanisms used by
eukaryotic cells to diversify their protein functions and dynamically coordinate their signaling …

Human pluripotent stem cells (hPSCs) are known to acquire genomic changes as they
proliferate and differentiate. Despite concerns that these changes will compromise the safety of …

The ends of chromosomes in Saccharomyces cerevisiae initiate a repressive chromatin
structure that spreads internally and inhibits the transcription of nearby genes, a phenomenon …

The brain is remarkable for its complex organization and functions, which have been
historically assumed to arise from cells with identical genomes. However, recent studies have …

Background Obesity and poor physical fitness constitute a health problem affecting an
increasing number of children. Causes include a pervasive “toxic” environment that facilitates …

… the cooperative learning data (Peterson & Miller, in press) indicate that perceived task
importance is highly predictive of students’ overall quality of experience (Peterson & Miller, 2002). …

The telomerase enzyme lengthens telomeres, an activity essential for chromosome stability
in most eukaryotes. The enzyme is composed of a specialized reverse transcriptase and a …

Down’s syndrome (DS), caused by trisomy of human chromosome 21, is the most common
genetic cause of intellectual disability. Here we use induced pluripotent stem cells (iPSCs) …

Significant barriers, such as lack of professional guidelines, specialized training for interpretation
of pharmacogenomics (PGx) data, and insufficient evidence to support clinical utility, …

OBJECTIVE: We sought to determine if periconceptional exposure to agrichemicals was
associated with the development of gastroschisis. STUDY DESIGN: We conducted a …