Background: To describe the history, clinical findings, and possible pathogenic etiologies of
the constellation of neuro-ophthalmic findings discovered in astronauts after long-duration …

Background: Several ophthalmic findings including optic disc swelling, globe flattening and
choroidal folds have been observed in astronauts following long-duration space flight. The …

Posterior globe flattening has been well-documented in astronauts both during and after
long-duration space flight (LDSF) and has been observed as early as 10 days into a mission on …

In high-performance aircraft, the need for total environmental awareness coupled with high-g
loading (often with abrupt onset) creates a predilection for cervical spine injury while the …

We previously reported a 57-year-old male astronaut who flew on his first 6-month space
mission in 2003 and his most recent flight in 2011–2012 (1). His first premission fundus …

Background: The diagnosis of cervical myelopathy is not always initially recognized. Only a
few reports have described the discrepancy between sensory level and the site of cord …

… Hart, MD … Mader TH, Gibson CR, Lee AG, Patel NB, Hart SF, Pettit DR. Unilateral loss
of spontaneous venous pulsations in an astronaut. J Neuroophthalmol. …

We greatly appreciate the opportunity to respond to the comments of Dr. Wostyn et al. Their
theory focuses on a glymphatic flow imbalance mechanism at the optic nerve head that may, …

Bacterial endotoxin inhibits the glucocorticoid induction of several hepatic enzymes including
phosphoenolpyruvate carboxykinase (PEPCK). Experiments were performed to elucidate …

In eukaryotes, conserved mechanisms ensure that cell growth is coordinated with nutrient
availability. Overactive growth during nutrient limitation leads to rapid cell death. Here, we …