User profiles for S. H. Merkling
Sarah MerklingResearch Faculty, CNRS, Institut Pasteur, Paris Verified email at pasteur.fr Cited by 4277 |
Beyond RNAi: antiviral defense strategies in Drosophila and mosquito
SH Merkling, RP van Rij - Journal of insect physiology, 2013 - Elsevier
Virus transmission and spread by arthropods is a major economic and public health concern.
The ongoing dissemination of arthropod-borne viruses by blood-feeding insects is an …
The ongoing dissemination of arthropod-borne viruses by blood-feeding insects is an …
Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients
…, F Pène, N Marin, N Roche, TA Szwebel, SH Merkling… - Science, 2020 - science.org
Coronavirus disease 2019 (COVID-19) is characterized by distinct patterns of disease
progression that suggest diverse host immune responses. We performed an integrated immune …
progression that suggest diverse host immune responses. We performed an integrated immune …
[HTML][HTML] Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection
…, J Hadjadj, N Yatim, H Pere, SH Merkling… - Nature …, 2021 - nature.com
Coordinated local mucosal and systemic immune responses following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against coronavirus …
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against coronavirus …
[PDF][PDF] Dicer-2-dependent generation of viral DNA from defective genomes of RNA viruses modulates antiviral immunity in insects
…, H Loyd, LI Levi, S Lanciano, C Baron, SH Merkling… - Cell Host & Microbe, 2018 - cell.com
The RNAi pathway confers antiviral immunity in insects. Virus-specific siRNA responses are
amplified via the reverse transcription of viral RNA to viral DNA (vDNA). The nature, …
amplified via the reverse transcription of viral RNA to viral DNA (vDNA). The nature, …
[HTML][HTML] Dissecting human population variation in single-cell responses to SARS-CoV-2
Humans display substantial interindividual clinical variability after SARS-CoV-2 infection 1 ,
2 – 3 , the genetic and immunological basis of which has begun to be deciphered 4 . …
2 – 3 , the genetic and immunological basis of which has begun to be deciphered 4 . …
[PDF][PDF] Non-retroviral endogenous viral element limits cognate virus replication in Aedes aegypti ovaries
…, P Miesen, L Frangeul, AB Crist, SH Merkling… - Current Biology, 2020 - cell.com
Endogenous viral elements (EVEs) are viral sequences integrated in host genomes. A large
number of non-retroviral EVEs was recently detected in Aedes mosquito genomes, leading …
number of non-retroviral EVEs was recently detected in Aedes mosquito genomes, leading …
[HTML][HTML] Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study
J Rosado, S Pelleau, C Cockram, SH Merkling… - The Lancet …, 2021 - thelancet.com
Background Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces an antibody response targeting multiple antigens that changes over time. This study …
induces an antibody response targeting multiple antigens that changes over time. This study …
A satellite repeat-derived piRNA controls embryonic development of Aedes
…, I Rondeel, B Pennings, CBF Vogels, SH Merkling… - Nature, 2020 - nature.com
Tandem repeat elements such as the diverse class of satellite repeats occupy large parts of
eukaryotic chromosomes, mostly at centromeric, pericentromeric, telomeric and subtelomeric …
eukaryotic chromosomes, mostly at centromeric, pericentromeric, telomeric and subtelomeric …
Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations
The drivers and patterns of zoonotic virus emergence in the human population are poorly
understood. The mosquito Aedes aegypti is a major arbovirus vector native to Africa that …
understood. The mosquito Aedes aegypti is a major arbovirus vector native to Africa that …
Cell-Fusing Agent Virus Reduces Arbovirus Dissemination in Aedes aegypti Mosquitoes In Vivo
Aedes aegypti mosquitoes are the main vectors of arthropod-borne viruses (arboviruses) of
public health significance, such as the flaviviruses dengue virus (DENV) and Zika virus (ZIKV)…
public health significance, such as the flaviviruses dengue virus (DENV) and Zika virus (ZIKV)…