Background Glycaemic control is a key issue in the care of people with diabetes mellitus (DM).
Some studies have suggested a bidirectional relationship between glycaemic control and …

Background Glycaemic control is a key issue in the care of people with diabetes mellitus (DM).
Periodontal disease is the inflammation and destruction of the underlying supporting …

… Sarah H Wild is senior lecturer in epidemiology and public health at the University of
Edinburgh. Christopher D Byrne is professor of endocrinology and metabolism at the University of …

Aims To provide global, regional, and country-level estimates of diabetes prevalence and
health expenditures for 2021 and projections for 2045. Methods A total of 219 data sources …

Uric acid is the end product of purine metabolism in humans and great apes, which have
lost hepatic uricase activity, leading to uniquely high serum uric acid concentrations (200–500 …

Estimating individual genome-wide autozygosity is important both in the identification of
recessive disease variants via homozygosity mapping and in the investigation of the effects of …

Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in
epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery …

Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies
have identified common CKD susceptibility variants. The CKDGen consortium performed …

Through genome-wide association meta-analyses of up to 133,010 individuals of European
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …

Metabolic disturbances associated with insulin resistance are present in most women with
polycystic ovary syndrome. This has led to suggestions that women with polycystic ovary …