The human leukocyte antigen (HLA) system encodes the human major histocompatibility
complex (MHC). HLA-B is the most polymorphic gene in the MHC class I region and many HLA-…

The human leukocyte antigen (HLA) system is a gene family that encodes the human major
histocompatibility complex (MHC). HLA-B is the most polymorphic gene in the MHC class I …

According to present estimations, the unfavorable combination of alleles with low penetrance
but high prevalence in the population might account for the major part of hereditary breast …

Dental caries, which affects billions of people, is a chronic infectious disease that involves
Streptococcus mutans, which is nevertheless a poor predictor of individual caries development…

Scavenger receptors are innate immune molecules recognizing and inducing the clearance
of non-host as well as modified host molecules. To recognize a wide pattern of invading …

The advent of next generation sequencing (NGS) has altered the face of genotyping the
human leukocyte antigen (HLA) system in clinical, stem cell donor registry, and research …

Human cell lines are essential tools for biological and medical research, such as models
predicting response to a treatment [1, 2], for identification of disease-specific biomarkers [3, 4], …

Background Gout is the most common cause of inflammatory arthritis worldwide, particularly
in Pacific regions. We aimed to establish the prevalence of gout and hyperuricaemia in …

Nanopore sequencing has been investigated as a rapid and cost-efficient option for HLA
typing in recent years. Despite the lower raw read accuracy, encouraging typing accuracy has …

Dental caries is a chronic infectious disease that affects billions of people with large individual
differences in activity. We investigated whether PRH1 and PRH2 polymorphisms in saliva …