Background The sinoatrial/sinus node (SAN) is the primary pacemaker of the heart. In
humans, SAN is surrounded by the paranodal area (PNA). Although the PNA function remains …

Atrial fibrillation (AF) is the most common cardiac arrhythmia. AF is thought to be triggered
by ectopic beats, originating primarily in the myocardial sleeves surrounding the pulmonary …

… work from our laboratory (Logantha, unpublished data). … with experimental work from our
laboratory (Logantha, … gradient is greater in magnitude in HF (Logantha, unpublished data). The …

This study used computer simulation to investigate the influence of heart failure (HF) on the
Purkinje fibre. The study was based on a rabbit model of HF caused by volume and pressure …

In the human, there is a circadian rhythm in the resting heart rate and it is higher during the
day in preparation for physical activity. Conversely, slow heart rhythms (bradyarrhythmias) …

… Research project related enquiries should be made in the first instance to Dr Sunil Jit Logantha
(sunil.logantha@liverpool.ac.uk). All general enquiries should be directed to Mrs Eleanor …

Purpose: The Popeye domain containing (Popdc) family of three novel muscle-restricted
genes (Popdc1-3) are evolutionarily conserved and expressed prominently within the cardiac …

Methods: Myocarditis was induced in BALB/c female mice. Animals were treated daily for two
weeks by intraperitoneal injection of vehicle, BML-111 (1 mg/kg daily), or luteolin (3’, 4’, 5, 7…

Background: Purkinje fibers (PFs) control timing of ventricular conduction and play a key role
in arrhythmogenesis in heart failure (HF) patients. We investigated the effects of HF on PFs. …

Background Atrial fibrillation (AF) often remains undetected following stroke. Documenting
AF is critical to initiate oral anticoagulation, which has proven benefit in reducing recurrent …