Sporadic Parkinson’s disease (PD) is a progressive neurodegenerative disease, with a
complex risk structure thought to be influenced by interactions between genetic variants and …

Eating disorders are complex heritable conditions influenced by both genetic and
environmental factors. Given the progress of genomic discovery in anorexia nervosa, with the …

… Sarah J Marzi Sarah J Marzi … Fredrika Åsenius, Amy F Danson, Sarah J Marzi, DNA methylation
in human sperm: a systematic review, Human Reproduction Update, Volume 26, Issue 6, …

We quantified genome-wide patterns of lysine H3K27 acetylation (H3K27ac) in entorhinal
cortex samples from Alzheimer’s disease (AD) cases and matched controls using chromatin …

Objective: DNA methylation has been proposed as an epigenetic mechanism by which early-life
experiences become “embedded” in the genome and alter transcriptional processes to …

Exposure to adverse rearing environments including institutional deprivation and severe
childhood abuse is associated with an increased risk for mental and physical health problems …

Background Ribosomal DNA (rDNA) displays substantial inter-individual genetic variation
in human and mouse. A systematic analysis of how this variation impacts epigenetic states …

Female mammals achieve dosage compensation by inactivating one of their two X
chromosomes during development, a process entirely dependent on Xist, an X-linked long non-…

Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance
our understanding of underlying mechanisms and pathways that can be targeted. We …

With the increase in large multimodal cohorts and high‐throughput technologies, the potential
for discovering novel biomarkers is no longer limited by data set size. Artificial intelligence …