Background Restless legs syndrome is a prevalent chronic neurological disorder with
potentially severe mental and physical health consequences. Clearer understanding of the …

Carotenoids are a category of health-promoting phytonutrients that are found in a variety of
fruits and vegetables and have been used as a biomarker to approximate dietary fruit and …

In multiple sclerosis (MS), lymphocyte—in particular B cell—transit between the central
nervous system (CNS) and periphery may contribute to the maintenance of active disease. …

Assessing children’s skin carotenoid score (SCS) using reflection spectroscopy (RS) is a
non-invasive, widely used method to approximate fruit and vegetable consumption (FVC). The …

Background Attention-deficit/hyperactivity disorder (ADHD) shows substantial heritability
and is two to seven times more common in male individuals than in female individuals. We …

Myeloproliferative neoplasms (MPNs) are blood cancers that are characterized by the
excessive production of mature myeloid cells and arise from the acquisition of somatic driver …

We trained and validated risk prediction models for the three major types of skin cancer—
basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and melanoma—on a cross-…

Complex traits, including migraine, often aggregate in families, but the underlying genetic
architecture behind this is not well understood. The aggregation could be explained by rare, …

Meiotic nondisjunction and resulting aneuploidy can lead to severe health consequences in
humans. Aneuploidy rescue can restore euploidy but may result in uniparental disomy (UPD…

Background Because residents of the southeastern United States experience disproportionally
high rates of cardiovascular disease (CVD), it is important to develop effective lifestyle …