Germline mutations of the BRCA1 and BRCA2 genes confer a high life-time risk of ovarian
cancer. They represent the most significant and well characterised genetic risk factors so far …

Context Approximately 10% of women with invasive epithelial ovarian cancer (EOC) carry
deleterious germline mutations in BRCA1 or BRCA2. A recent article suggested that BRCA2 -…

Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …

Polycomb group proteins (PCGs) are involved in repression of genes that are required for
stem cell differentiation. Recently, it was shown that promoters of PCG target genes (PCGTs) …

Background: Previously, small studies have found that BRCA1 and BRCA2 breast tumors
differ in their pathology. Analysis of larger datasets of mutation carriers should allow further …

The present study investigates whether the ability to classify on the basis of rules can be
learned independently of memory for the specific instances used to leach the rules. Thirteen …

Background: Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy,
responsible for 13 000 deaths per year in the United States. Risk prediction based on …

Background Few biomarkers of ovarian cancer prognosis have been established, partly
because subtype-specific associations might be obscured in studies combining all …

The recognition that certain aspects of prefrontal function can be effectively modeled in rats
has led to a slow expansion of interest in rat prefrontal cortex over the past decade. One of …

Genome-wide association studies (GWAS) have identified four susceptibility loci for
epithelial ovarian cancer (EOC), with another two suggestive loci reaching near genome-wide …