A fundamental physical interaction exists across the synapse. It is mediated by synaptic
adhesion molecules, and is among the earliest and most indispensable of molecular events …

… Now Seth Shipman and colleagues report a quantitative leap in this direction. They have
encoded a motion picture into the DNA of a population of Escherichia coli by storing pixel …

Highlights • Molecular recorders capture transcriptional activity within the genome of cells. •
Transcriptional activity is recorded by linking a signal of interest to a DNA writer. • …

INTRODUCTION Although recent advances in DNA synthesis and sequencing technologies
have made practical the writing and readout of arbitrary data in the form of synthetic DNA, …

Advances in cellular reprogramming and stem cell differentiation now enable ex vivo
studies of human neuronal differentiation. However, it remains challenging to elucidate the …

Human pluripotent stem cells (hPSCs) offer an unprecedented opportunity to model diverse
cell types and tissues. To enable systematic exploration of the programming landscape …

Fenestral and stomatal diaphragms are endothelial subcellular structures of unknown function
that form on organelles implicated in vascular permeability: fenestrae, transendothelial …

Neuroligins, a family of postsynaptic adhesion molecules, are important in synaptogenesis
through a well-characterized trans-synaptic interaction with neurexin. In addition, neuroligins …

Exogenous DNA can be a template to precisely edit a cell’s genome. However, the delivery
of in vitro-produced DNA to target cells can be inefficient, and low abundance of template …

At neuronal excitatory synapses, two major subtypes of the synaptic adhesion molecule
neuroligin are present. These subtypes, neuroligin 1 and neuroligin 3, have roles in …