The lipid layer is an essential component of the tear film, providing a smooth optical surface
for the cornea and retarding evaporation from the eye. The meibomian lipids which compose …

Microtubules are filamentous polymers essential for cell viability. Microtubule plus-end tracking
proteins (+TIPs) associate with growing microtubule plus ends and control microtubule …

Dendritic spines are the major sites of excitatory synaptic input, and their morphological
changes have been linked to learning and memory processes. Here, we report that growing …

Stromal interaction molecule 1 (STIM1) is a transmembrane protein that is essential for store-operated
Ca 2+ entry, a process of extracellular Ca 2+ influx in response to the depletion of …

End binding proteins (EBs) are highly conserved core components of microtubule plus-end
tracking protein networks. Here we investigated the roles of the three mammalian EBs in …

Microtubule plus-end tracking proteins (+TIPs) are structurally and functionally diverse factors
that accumulate at the growing microtubule plus-ends, connect them to various cellular …

The kinesin-13 family member mitotic centromere-associated kinesin (MCAK) is a potent
microtubule depolymerase [1–4]. Paradoxically, in cells it accumulates at the growing, rather …

Centrioles are very small microtubule-based organelles essential for centrosome, cilia and
flagella assembly, which are involved in a variety of cellular and developmental processes. …

The ends of growing microtubules (MTs) accumulate a set of diverse factors known as MT
plus end–tracking proteins (+TIPs), which control microtubule dynamics and organization. In …

Dynamic microtubules are important to maintain neuronal morphology and function, but whether
neuronal activity affects the organization of dynamic microtubules is unknown. Here, we …