A Western lifestyle with high salt consumption can lead to hypertension and cardiovascular
disease. High salt may additionally drive autoimmunity by inducing T helper 17 (T H 17) cells…

Centenarians have a decreased susceptibility to ageing-associated illnesses, chronic
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct gut …

Industrialization has impacted the human gut ecosystem, resulting in altered microbiome
composition and diversity. Whether bacterial genomes may also adapt to the industrialization of …

Our understanding of how the gut microbiome interacts with its human host has been
restrained by limited access to longitudinal datasets to examine stability and dynamics, and by …

Wound healing capability is inextricably linked with diverse aspects of physical fitness
ranging from recovery after minor injuries and surgery to diabetes and some types of cancer. …

A recent epidemiological study showed that eating ‘fast food’ items such as potato chips
increased likelihood of obesity, whereas eating yogurt prevented age-associated weight gain in …

Microbial communities and their associated bioactive compounds 1 , 2 – 3 are often disrupted
in conditions such as the inflammatory bowel diseases (IBD) 4 . However, even in well-…

Background Health systems and providers across America are increasingly employing
telehealth technologies to better serve medically underserved low-income, minority, and rural …

The gut microbiome is a dynamic system that changes with host development, health,
behavior, diet, and microbe-microbe interactions. Prior work on gut microbial time series has …

Increased levels of proteases, such as trypsin, in the distal intestine have been implicated in
intestinal pathological conditions 1 , 2 – 3 . However, the players and mechanisms that …