User profiles for S. M. Mount

Stephen M. Mount

Associate Professor, Dept. of Cell Biology and Molecular Genetics, University of Maryland
Verified email at umd.edu
Cited by 26048

The Genome Sequence of Drosophila melanogaster

…, C Mobarry, J Morris, A Moshrefi, SM Mount… - Science, 2000 - science.org
The fly Drosophila melanogaster is one of the most intensively studied organisms in biology
and serves as a model system for the investigation of many developmental and cellular …

A catalogue of splice junction sequences

SM Mount - Nucleic acids research, 1982 - academic.oup.com
Splice junction sequences from a large number of nuclear and viral genes encoding protein
have been collected. The sequence A C AG/GT G A AGT was found to be a consensus of …

Are snRNPs involved in splicing?

MR Lerner, JA Boyle, SM Mount, SL Wolin, JA Steitz - Nature, 1980 - nature.com
… Ehrlich ascites cell nuclei, whereas anti-Sm antibodies bind these snRNPs and four
others … observations) using anti-RNP and anti-Sm sera confirm the nuclear (but non-nucleolar) …

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, P Minx, MU Mollenhauer, K Montooth, SM Mount… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies

BJ Haas, AL Delcher, SM Mount… - Nucleic acids …, 2003 - academic.oup.com
The spliced alignment of expressed sequence data to genomic sequence has proven a key
tool in the comprehensive annotation of genes in eukaryotic genomes. A novel algorithm …

[HTML][HTML] The draft genome of the transgenic tropical fruit tree papaya (Carica papaya Linnaeus)

…, MC Luo, L Liu, DA Christopher, SM Mount… - Nature, 2008 - nature.com
Papaya, a fruit crop cultivated in tropical and subtropical regions, is known for its nutritional
benefits and medicinal applications. Here we report a 3× draft genome sequence of ‘SunUp’ …

Sailfish enables alignment-free isoform quantification from RNA-seq reads using lightweight algorithms

R Patro, SM Mount, C Kingsford - Nature biotechnology, 2014 - nature.com
We introduce Sailfish, a computational method for quantifying the abundance of previously
annotated RNA isoforms from RNA-seq data. Because Sailfish entirely avoids mapping reads…

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

SM Mount, I Pettersson, M Hinterberger, A Karmas… - Cell, 1983 - cell.com
The ability of purified Ul small nuclear RNA-protein complexes (Ul snRNPs) to bind in vitro
to two RNAs transcribed from recombinant DNA clones by bacteriophage T7 RNA …

[HTML][HTML] Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis

MA Campbell, BJ Haas, JP Hamilton, SM Mount… - BMC genomics, 2006 - Springer
Background Recently, genomic sequencing efforts were finished for Oryza sativa (cultivated
rice) and Arabidopsis thaliana (Arabidopsis). Additionally, these two plant species have …

Reducing storage requirements for biological sequence comparison

M Roberts, W Hayes, BR Hunt, SM Mount… - …, 2004 - academic.oup.com
Motivation: Comparison of nucleic acid and protein sequences is a fundamental tool of
modern bioinformatics. A dominant method of such string matching is the ‘seed-and-extend’ …