Mucosal melanoma (MM) is an aggressive and clinically complex malignancy made more
challenging by its relative rarity. Because of the rarity of MM as a whole, and because of the …

Background Previous results from our phase 3 randomised trial showed that adding
cetuximab to primary radiotherapy increased overall survival in patients with locoregionally …

Physiological platelet synthesis is thought to require the humoral activities of meg-CSF and
thrombopoietin, which respectively promote proliferation and maturation of megakaryocytic …

… Spencer et al., manuscript in preparation). Arrows indicate the top of the resolving gels. a, 1
J.… Sa) containing a cytomegalovirus promoter and the other functions necessary for high level …

Purpose: The optimal fractionation schedule for radiotherapy of head and neck cancer has
been controversial. The objective of this randomized trial was to test the efficacy of …

Human tumor necrosis factor (TNF) was purified to homogeneity from serum-free tissue culture
supernatants of the HL-60 promyelocytic leukemia cell line induced by 4 beta-phorbol 12-…

One of the reasons for advocating human milk (HM) feeding for preterm infants is the belief
that this provides the infant with a degree of protection from infection. Providing fresh HM for …

Objectives To test the hypothesis that somatic phosphatidylinositol-4,5-bisphospate 3-kinase,
catalytic subunit alpha (PIK3CA) mutations would be found in patients with more common …

PURPOSE: To evaluate the safety, pharmacokinetics, and efficacy of a chimeric anti–epidermal
growth factor receptor monoclonal antibody, cetuximab, in combination with radiation …

Efforts have been made to find new, non-invasive methods for assessing tissue oxygenation
and haemodynamics, particularly in the brain of the fetus and the newborn infant. Near …