[HTML][HTML] OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines

W Zhang, RW Moskowitz, G Nuki, S Abramson… - Osteoarthritis and …, 2008 - Elsevier
PURPOSE: To develop concise, patient-focussed, up to date, evidence-based, expert
consensus recommendations for the management of hip and knee osteoarthritis (OA), which are …

[HTML][HTML] OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research …

W Zhang, G Nuki, RW Moskowitz, S Abramson… - Osteoarthritis and …, 2010 - Elsevier
OBJECTIVE: To update evidence for available therapies in the treatment of hip and knee
osteoarthritis (OA) and to examine whether research evidence has changed from 31 January …

Cyclooxygenase in biology and disease

RN Dubois, SB Abramson, L Crofford… - The FASEB …, 1998 - Wiley Online Library
Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to
prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit …

Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials.

N Bhala, J Emberson, A Merhi, S Abramson… - Lancet (London …, 2013 - europepmc.org
… N Arber, M Farkouh, PM Kearney, P Lance and S Solomon declare that they have no conflicts
of interest. S Abramson serves as a consultant to Abbott and Pfizer. JA Baron was formerly …

[HTML][HTML] OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of …

W Zhang, RW Moskowitz, G Nuki, S Abramson… - Osteoarthritis and …, 2007 - Elsevier
PURPOSE: As a prelude to developing updated, evidence-based, international consensus
recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis …

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

…, T Rostron, V Cerundolo, EG Pamer, SB Abramson… - elife, 2013 - elifesciences.org
10.7554/eLife.01202.001 Rheumatoid arthritis (RA) is a prevalent systemic autoimmune
disease, caused by a combination of genetic and environmental factors. Animal models suggest …

Connective tissue growth factor mediates transforming growth factor β‐induced collagen synthesis: down‐regulation by cAMP

…, KS Frazier, S Abramson, S Williams… - The FASEB …, 1999 - Wiley Online Library
Connective tissue growth factor (CTGF) is a cysteine‐rich peptide synthesized and secreted
by fibroblastic cells after activation with transforming growth factor beta (TGF‐β) that acts as …

[PDF][PDF] Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets

…, J Martel‐Pelletier, SB Abramson - Arthritis & Rheumatism …, 2001 - stem-art.com
… The selection or combination of the gene(s) that would offer the best protection against OA
remains to be determined. The transfer of genes such as IL-1Ra, IL-10, and IL-13 has been …

Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease

…, EG Pamer, DR Littman, SB Abramson - Arthritis & …, 2015 - Wiley Online Library
… For each sample, microbial diversity was estimated by calculating the Shannon diversity
index or Faith’s phylodiversity index. Phylogenetic classification was performed using the …

Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase.

…, J Leszczynska-Piziak, SB Abramson - The Journal of clinical …, 1992 - Am Soc Clin Investig
… initiation resulted in a 30-s lag before the detection of O. … with its short halflife (t < 15 s) in
oxygenated solution. Thus, nitric … detection of superoxide anion for 30 s. Thereafter, in contrast to …